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Shende Jiang ——Professor

Previous Room A509 (Note: office currently uncertain duo to building renovation and space redistribution), Building 24, Tianjin University
School of Pharmaceutical Science and Technology
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Education Experience
1979-1983 B.Sc. Chemistry Liaocheng Normal College
1983-1986 Master of Science Medicinal Chemistry Shandong Medical University
1992-1996 Doctor of Philosophy Organic Chemistry University of Teesside
Professional Experience
1986-1988 Lecturer Shandong Normal University
1988-1990 Leverhulme Trust Research Fellow Department of Continuing Education, University of Nottingham
1990-1991 Leverhulme Trust Research Fellow Department of Chemistry, University of Nottingham
1991-1992 Research Fellow Department of Chemistry, Nottingham Polytechnic
1996-2002 Postdoc Researcher School of Pharmacy, University of Sunderland
2002-2003 Research Associate Heriot-Watt University
2003-2004 Research Associate University of Newcastle upon Tyne
2004- Professor of Medicinal Chemistry Tianjin University
Research Area

The research of the Jiang group includes, a) carbohydrate chemistry with the use of sugars as chiral starting materials in synthesis, b) studies on the shikimic acid and shikimate pathway with particular interests in designing enzyme inhibitors as potential antimicrobial agents against bacterial, fungal and parasitical pathogens, c) process research and development for Active Pharmaceutical Ingredients and related intermediates in collaboration with industry, and d) development of fluorine-18 labelled radiopharmaceuticals used in Positron Emission Tomography


Honors and Awards
Highlighted Publications
Yao, S.; Hu, K.; Tang, G.; Liang, X.; Du, K.; Nie, D.; Jiang, S.; Zang, L. Positron emission tomography imaging of cell death with [18F]FPDuramycin. Apoptosis 2014, 19, 841.
Liu, C.; Kang, H.; Wightman, R. H.; Jiang, S. Stereoselective synthesis of a novel Galf-disaccharide mimic:β-D-galactofuranosyl-(1-5)-β-D-galactofuranosyl motif of mycobacterial cell walls. Tetrahedron Lett. 2013, 54, 1192.
Wang, H.; Guo, X.; Jiang, S.; Tang, G. Automated synthesis of [18F] Florbetaben as Alzheimer’s disease imaging agent based on a synthesis module system. Appl. Radiat. Isotopes 2013, 71, 41.
Geng, H.; Chen, J. L-Y.; Furkert, D. P.; Jiang, S.; Brimble, M. A. A Covergent Synthesis of the 2-Formylpyrrole Spiroketal Natural Product Acortatarin A. Synlett 2012, 23, 855.
Wang, H.; Shi, H.; Yu, H.; Jiang S.; Tang, G. Facile and rapid one-step radiosynthesis of [18F]BAY94-9172 with a new precursor. Nucl. Med. Biol. 2011, 38, 121.
ResearcherID Publications
Year Title Author(s) Source Volume
2015 Lewis Acid Catalyzed Intramolecular [3 2] Cross Cycloadditions of Cobalt-Alkynylcyclopropane 1,1-Diesters with Carbonyls for Construction of Medium-Sized and Polycyclic Skeletons Zhang, Junhui; Xing, Siyang; Ren, Jun; et al. Organic Letters 17
2015 Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with 18F-ML-8. Yao, Shaobo; Hu, Kongzhen; Tang, Ganghua; et al. BioMed research international 2015
2015 Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with F-18-ML-8 Yao, Shaobo; Hu, Kongzhen; Tang, Ganghua; et al. Biomed Research International
2014 Positron emission tomography imaging of cell death with [F-18]FPDuramycin Yao, Shaobo; Hu, Kongzhen; Tang, Ganghua; et al. Apoptosis 19
2014 Synthesis and Antimetastatic Effects of E-Salignone Amide Derivatives Wang, Hong-Ling; Qin, Nan; Liu, Jia; et al. Drug Development Research 75
2005 Plasmodium falciparum: Interaction of shikimate analogues with antimalarial drugs McRobert, L; Jiang, SD; Stead, A; et al. Experimental Parasitology 111
2005 Synthesis of (6S)-fluoroshikimic acid (Retraction of vol 14, pg 2833, 2003) Song, CJ; Jiang, SD; Singh, G Tetrahedron-Asymmetry 16
2004 Syntheses of ethyl 3-deoxy-3,3-difluoro-D-arabino-heptulosonate and analogues Li, Y; Drew, MGB; Welchman, EV; et al. Tetrahedron 60
2003 Synthesis of (6S)-6-fluoroshikimic acid (Retracted Article. See vol 16, pg. 2832, 2005) Song, C; Jiang, S; Singh, G Tetrahedron-Asymmetry 14
2002 Facile syntheses of (6S)-6-fluoroshikimic acid and (6R)-6-hydroxyshikimic acid Song, CJ; Jiang, SD; Singh, GD Chemical Research in Chinese Universities 18
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