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Jianhui Huang——Professor

Office 504C, Building 24, Tianjin University
School of Pharmaceutical Science and Technology
Group weblink
Education Experience
2003-2006 Doctor of Philosophy  Chemistry University of York, UK
1996-2000 Bachelor of Science Chemistry Hu'nan University
Professional Experience
2000-2003 Research Associate Tianjin Institute of Pharmaceutical Research,China
2007-2010 Post-doctorial Research Associate University of Sheffield and GlaxoSmithKlein
2010-2017 Associate Professor Tianjin University, China
2017- Professor Tianjin University
Research Area

The research of the Huang group encompasses three main areas:  1) Studies towards the synthesis of heterocycles via transition metal catalysis, 


2) Design and synthesis of useful active pharmaceutical ingredients, and 

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3) Late-stage functionalization of drug molecules and other materials.

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Honors and Awards
Thieme Chemistry Journal Award, 2017
Best Publication Award, HSP, Tianjin University, 2015
钌催化下的2-(3-溴苯基)吡啶类衍生物的合成, 2015031900635430, 黄剑辉、于庆贞、胡乐安、王悦、赵康, 2016.09
2-取代乙烯醇甲酸酯类衍生物的制备方法, 201210441980X, 黄剑辉、杨丹、丁诗璇、赵康, 2014.07
3-羟基-2-烷氧基-3-苯基异吲哚-1(2H)-酮类衍生物的制备方法, 2013102117068, 黄剑辉、刘伟东、朱怡、于庆贞、张娜娜, 2015.07
Highlighted Publications
R. Zhu; Z. Liu; J. Chen; X. Xiong; Y. Wang; L. Huang; J. Bai; Y. Dang; J. Huang ” The preparation of thioanisole biscarbanion and C–H lithiation/annulation reactions for the access of five-membered heterocycles” Org. Lett., 2018, 3161-3165.
Y. Wang; J. Liu; L. Huang; R. Zhu; X. Huang; R. Moir and J. Huang "KOtBu-catalyzed lithiation of PMDTA and the direct functionalization of bridged alkenens under mild conditions." Chem. Commun., 2017, 53, 4589-4592.
Z. Chen; L. Hu; F. Zeng; R. Zhu; S. Zheng; Q. Yu and J. Huang "Selective mono-alkylation of N-methoxybenzamides." Chem. Commun., 2017, 53, 4258-4261.
Q. Yu; L. Hu; Y. Wang; S. Zheng; J. Huang "Directed meta-selective bromination of arenes with ruthenium catalysts." Angew. Chem. Int. Ed., 2015, 54, 15284-15288.
W. Liu; Q. Yu; L. Hu; J. Huang "Modular synthesis of dihydro-isoquinolines: palladium-catalyzed sequential C(sp2)-H and C(sp3)-H bond activation." Chem. Sci., 2015, 6, 5768-5772.
Zhong, H.; Yang, D.; Wang, S.; Huang, J. Pd-catalyzed synthesis of isoquinolinones and analogues via C-H and N-H bonds double activation. Chem. Commun. 2012, 48, 3236.
ResearcherID Publications
Year Title Author(s) Source Volume
2012 Synthesis of N-alkyl and N-aryl isoquinolones and derivatives via Pd-catalysed C-H activation and cyclization reactions Zhang, Nana; Li, Binyao; Zhong, Hongban; et al. Organic & Biomolecular Chemistry 10
2012 Synthesis of Functionalized Fluorescent Indenes from Electron-Rich alpha-Aryl Ketonitriles Liu, Le; Fan, Yanfeng; He, Qiaoqiao; et al. Journal of Organic Chemistry 77
2012 Pd-catalysed synthesis of isoquinolinones and analogues via C-H and N-H bonds double activation Zhong, Hongban; Yang, Dan; Wang, Songqing; et al. Chemical Communications 48
2012 Copper(II)-Mediated Cascade Oxidative C-C Coupling and Aromatization: Synthesis of 3-Hydroxyphenanthridinone Derivatives Yu, Qingzhen; Zhang, Nan; Tang, Yang; et al. Synthesis-Stuttgart 44
2013 Synthesis of biaryl imino/keto carboxylic acids via aryl amide directed C-H activation reaction Zhang, Nana; Yu, Qingzhen; Chen, Ruixue; et al. Chemical Communications 49
2013 Pd-catalysed direct dehydrogenative carboxylation of alkenes: facile synthesis of vinyl esters Yang, Dan; Ding, Shixuan; Huang, Jianhui; et al. Chemical Communications 49
2013 Isoquinoline N-Oxide Synthesis under Pd-Catalysed C-H Activation/Annulation Processes Li, Bingyao; Jiao, Pingxuan; Zhong, Hongban; et al. Synlett 24
2013 Efficient Synthesis of Hydroxyl Isoindolones by a Pd-Mediated C-H Activation/Annulation Reaction Yu, Qingzhen; Zhang, Nana; Huang, Jianhui; et al. Chemistry-a European Journal 19
2013 A practical one-pot procedure for the synthesis of N-H isoquinolones Lu, Shaonan; Lin, Yingfu; Zhong, Hongban; et al. Tetrahedron Letters 54
2015 Modular synthesis of dihydro-isoquinolines: palladium-catalyzed sequential C(sp(2))-H and C(sp(3))-H bond activation Liu, W. D.; Yu, Q. Z.; Hu, L. A.; et al. Chemical Science 6
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