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Jianhui Huang——Professor

Office 504C, Building 24, Tianjin University
School of Pharmaceutical Science and Technology
Group weblink
Education Experience
2003-2006 Doctor of Philosophy  Chemistry University of York, UK
1996-2000 Bachelor of Science Chemistry Hu'nan University
Professional Experience
2000-2003 Research Associate Tianjin Institute of Pharmaceutical Research,China
2007-2010 Post-doctorial Research Associate University of Sheffield and GlaxoSmithKlein
2010-2017 Associate Professor Tianjin University, China
2017- Professor Tianjin University
Research Area

The research of the Huang group encompasses three main areas:  1) Studies towards the synthesis of heterocycles via transition metal catalysis, 


2) Design and synthesis of useful active pharmaceutical ingredients, and 

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3) Late-stage functionalization of drug molecules and other materials.

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Honors and Awards
Thieme Chemistry Journal Award, 2017
Best Publication Award, HSP, Tianjin University, 2015
钌催化下的2-(3-溴苯基)吡啶类衍生物的合成, 2015031900635430, 黄剑辉、于庆贞、胡乐安、王悦、赵康, 2016.09
2-取代乙烯醇甲酸酯类衍生物的制备方法, 201210441980X, 黄剑辉、杨丹、丁诗璇、赵康, 2014.07
3-羟基-2-烷氧基-3-苯基异吲哚-1(2H)-酮类衍生物的制备方法, 2013102117068, 黄剑辉、刘伟东、朱怡、于庆贞、张娜娜, 2015.07
Highlighted Publications
R. Zhu; Z. Liu; J. Chen; X. Xiong; Y. Wang; L. Huang; J. Bai; Y. Dang; J. Huang ” The preparation of thioanisole biscarbanion and C–H lithiation/annulation reactions for the access of five-membered heterocycles” Org. Lett., 2018, 3161-3165.
Y. Wang; J. Liu; L. Huang; R. Zhu; X. Huang; R. Moir and J. Huang "KOtBu-catalyzed lithiation of PMDTA and the direct functionalization of bridged alkenens under mild conditions." Chem. Commun., 2017, 53, 4589-4592.
Z. Chen; L. Hu; F. Zeng; R. Zhu; S. Zheng; Q. Yu and J. Huang "Selective mono-alkylation of N-methoxybenzamides." Chem. Commun., 2017, 53, 4258-4261.
Q. Yu; L. Hu; Y. Wang; S. Zheng; J. Huang "Directed meta-selective bromination of arenes with ruthenium catalysts." Angew. Chem. Int. Ed., 2015, 54, 15284-15288.
W. Liu; Q. Yu; L. Hu; J. Huang "Modular synthesis of dihydro-isoquinolines: palladium-catalyzed sequential C(sp2)-H and C(sp3)-H bond activation." Chem. Sci., 2015, 6, 5768-5772.
Zhong, H.; Yang, D.; Wang, S.; Huang, J. Pd-catalyzed synthesis of isoquinolinones and analogues via C-H and N-H bonds double activation. Chem. Commun. 2012, 48, 3236.
ResearcherID Publications
Year Title Author(s) Source Volume
2018 Preparation of Thioanisole Biscarbanion and C-H Lithiation/Annulation Reactions for the Access of Five-Membered Heterocycles Zhu, Ranran; Liu, Zheyuan; Chen, Jie; et al. Organic Letters 20
2018 Norbornene in Organic Synthesis Li, Caifeng; Liu, Liu; Fu, Xuegang; et al. Synthesis-Stuttgart 50
2018 Direct Double Arylation of Bridged Alkenes and Efficient Bis-C-H Alkylation of Benzamides Zhao, Xiaoxia; Bai, Jinshan; Zeng, Fanyun; et al. Chemistryselect 3
2008 A [4 2] cycloaddition strategy to pyridine boronic ester derivatives Delaney, Patrick M.; Huang, Jianhui; Macdonald, Simon J. F.; et al. Organic Letters 10
2006 Two-step synthesis of N-sulfonyl aziridines from epoxides Huang, JH; O’Brien, P Synthesis-Stuttgart
2005 Organolithium-mediated conversion of beta-functionalised aziridines into alkynyl amino alcohols and diamines Huang, JH; O’Brien, P Chemical Communications
2005 Two-step syntheses of 2,4,6-triisopropylbenzenesulfonyl aziridines Huang, JH; O’Brien, P Tetrahedron Letters 46
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