Home / People / Faculty / Donghua Wang

Donghua Wang ——Associate Professor

Nationality:
CHINA
Phone:
022-27409967
Email:
wdh022@tju.edu.cn
Office:
Room 446, Building 11, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2006 Ph. D. Tianjin University, CN
Professional Experience
1998-2004 lecturer Tianjin University
1996-1998 assistant Tianjin University
2004-2015 associate professor Tianjin University
Research Area

The research in the group of Wang involves the design, synthesis, and biological activity evaluation of new compounds, with focus on industrialization of generic drugs, intermediates, and fine chemicals.  Specific areas include 1) Design and synthesis of the Rho kinase inhibitor, 2) Design and synthesis of the PDE4 inhibitor, and 3) Design and synthesis of antihistamine drugs

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Honors and Awards
Patents
Highlighted Publications
Lin,Y.; Wang, Y.; Sima, L-F.; Wang, D.-H.; Cao, X.-H.; Chen, L.-G.; Chen, B. Design, synthesis and biological activity evaluation of desloratadine analogues as H-1 receptor antagonists. Bioorgan. Med. Chem. 2013, 21, 4178.
Lin,Y.; Huang, P.; Liu, S.; Sima, L.; Chen, L.; Wang, D.A convenient method for the synthesis of roflumilast. Res. Chem. Intermed. 2013, 39, 2107.
Chen, M.; Liu, S.; Wang, X.; Luo, H.; Chen, L.; Wang, D. Synthesis of 1-Isoquinolinol and Hydroxyfasudil. Chin. J. Org. Chem. 2012, 32, 404.
Wang, Y.; Wang, J.; Lin, Y.; Si-Ma, L.-F.; Wang, D.-H. Chen, L.-G.; Deng-Ke, L. Synthesis and Antihistamine Evaluations of Novel Loratadine Analogues. Bioorgan. Med. Chem. 2011, 21, 4454.
Wang, D.; Qu, W.; Shi, L.; Wei, J. Molecular Docking and Pharmacophore Model Studies of Rho Kinase Inhibitors. Mol. Simulat. 2011, 37, 488.
ResearcherID Publications
Year Title Author(s) Source Volume
2011 Molecular docking and pharmacophore model studies of Rho kinase inhibitors Wang, Dong-Hua; Qu, Wan-Lu; Shi, Liu-Qing; et al. Molecular Simulation 37
2011 Synthesis and antihistamine evaluations of novel loratadine analogues Wang, Yue; Wang, Juan; Lin, Yan; et al. Bioorganic & Medicinal Chemistry Letters 21
2011 Synthesis and antihistamine evaluations of novel loratadine analogues (vol 21, pg 4454, 2011) Wang, Yue; Wang, Juan; Lin, Yan; et al. Bioorganic & Medicinal Chemistry Letters 21
2010 The role of iron in the selective amination of 1,2-butanediol to 2-amino-1-butanol over Co-Ba-Fe/gamma-Al2O3 Zhao, Guangle; Yu, Liang; Yan, Xilong; et al. Reaction Kinetics Mechanisms and Catalysis 100
2009 Preparation of polystyrene fluorescent microspheres based on some fluorescent labels Liu, Qing-Hao; Liu, Jia; Guo, Jin-Chun; et al. Journal of Materials Chemistry 19
2009 Selective Hydrolysis and Decarboxylation of Methyl [1-(2-Cyanoethyl)-2-oxocyclopentyl]carboxylate Zhao Guangle; Yu Liang; Yan Xilong; et al. Chinese Journal of Organic Chemistry 29
2009 Spectrofluorimetric determination of trace nitrite with a novel fluorescent probe Liu, Qing-Hao; Yan, Xi-Long; Guo, Jin-Chun; et al. Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy 73
2009 Synthesis of 6,7-Dihydro-5H-1-pyrindine Chen Yanxue; Zhao Guangle; Li Yang; et al. Chinese Journal of Organic Chemistry 29
2005 Novel approach to 3-methyl-1H-quinoxalin-2-ones Li, X; Wang, DH; Wu, JF; et al. Synthetic Communications 35
2005 Synthesis of substituted 1,3-dimethyl-1H-quinoxalin-2-ones from aniline derivatives Li, X; Wang, DH; Wu, JF; et al. Heterocycles 65
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