Home / People / Faculty / Donghua Wang

Donghua Wang ——Associate Professor

Nationality:
CHINA
Phone:
022-27409967
Email:
wdh022@tju.edu.cn
Office:
Room 446, Building 11, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2006 Ph. D. Tianjin University, CN
Professional Experience
1998-2004 lecturer Tianjin University
1996-1998 assistant Tianjin University
2004-2015 associate professor Tianjin University
Research Area

The research in the group of Wang involves the design, synthesis, and biological activity evaluation of new compounds, with focus on industrialization of generic drugs, intermediates, and fine chemicals.  Specific areas include 1) Design and synthesis of the Rho kinase inhibitor, 2) Design and synthesis of the PDE4 inhibitor, and 3) Design and synthesis of antihistamine drugs

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Honors and Awards
Patents
Highlighted Publications
Lin,Y.; Wang, Y.; Sima, L-F.; Wang, D.-H.; Cao, X.-H.; Chen, L.-G.; Chen, B. Design, synthesis and biological activity evaluation of desloratadine analogues as H-1 receptor antagonists. Bioorgan. Med. Chem. 2013, 21, 4178.
Lin,Y.; Huang, P.; Liu, S.; Sima, L.; Chen, L.; Wang, D.A convenient method for the synthesis of roflumilast. Res. Chem. Intermed. 2013, 39, 2107.
Chen, M.; Liu, S.; Wang, X.; Luo, H.; Chen, L.; Wang, D. Synthesis of 1-Isoquinolinol and Hydroxyfasudil. Chin. J. Org. Chem. 2012, 32, 404.
Wang, Y.; Wang, J.; Lin, Y.; Si-Ma, L.-F.; Wang, D.-H. Chen, L.-G.; Deng-Ke, L. Synthesis and Antihistamine Evaluations of Novel Loratadine Analogues. Bioorgan. Med. Chem. 2011, 21, 4454.
Wang, D.; Qu, W.; Shi, L.; Wei, J. Molecular Docking and Pharmacophore Model Studies of Rho Kinase Inhibitors. Mol. Simulat. 2011, 37, 488.
ResearcherID Publications
Year Title Author(s) Source Volume
2004 An efficient approach to 6, 7-disubstituted-1H-quinoxalin-2-ones Li, X; Hu, QP; Cui, XG; et al. Chinese Chemical Letters 15
2004 An improved synthesis of 6-chloro-1H-quinoxalin-2-one Li, X; Hu, QP; Cui, XG; et al. Chinese Journal of Organic Chemistry 24
2004 Tetra-mu-acetato-kappa O-8 : O ’-bis[(2-benzylidene-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-one-kappa N)cobalt(II)] Wang, DH; Li, X; Liu, XG Acta Crystallographica Section E-Structure Reports Online 60
2002 Studies into the aqueous properties of hydroxyglycine Pan, FG; Wang, DH; Fang, F; et al. Chinese Journal of Organic Chemistry 22
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