Home / People / / Yanjun Zhao

Yanjun Zhao ——Professor

Nationality:
CHINA
Phone:
022-27407882
Email:
zhaoyj@tju.edu.cn
Office:
Room 412-1, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2005-2010 Ph. D. Pharmacy King’s College London, UK
2002-2005 M.S. Biochemical Engineering Dalian Institute of Chemical Physics, CAS
1998-2002 Bachelor Polymer Dalian University of Technology
Professional Experience
2009-2009 Research Scientist MedPharm Ltd. (UK)
2010-2012 Lecturer Tianjin University, China
2012-2018 Associate Professor Tianjin University, China
2018- Professor Tianjin University, China
Research Area

The research in the group of Zhao encompasses four main areas, including (1) Stimuli-responsive drug delivery systems; (2) Ferroptosis-targeting nanomedicines; (3) Photo-triggered microtubule inhibitors; (4) Pharmaceutical micelles, biomaterials and nanomaterials.

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Honors and Awards
2013: Tianjin University “Elite Scholar”
2009: Chinese Government Award for Outstanding Self-financed Students Abroad
2005: Dorothy Hodgkin Postgraduate Awards
Patents
CN Patent: ZL 2013 1 0755965.7
CN Patent: ZL 2014 1 0008911.9
Highlighted Publications
Deng J, Liu F, Wang L, An Y, Gao M, Wang Z, Zhao Y. Hypoxia- and singlet oxygen-responsive chemo-photodynamic micelles featured with glutathione depletion and aldehyde production. Biomater Sci, 2019, 7(1):429-441.
Liu G, Deng J, Liu F, Wang Z, Peer D, Zhao Y. Hierarchically theranostic nanomedicine: MRI contrast agents as the physical vehicle anchor for high drug loading and triggered on-demand delivery. J Mater Chem B, 2018, 6(13): 1995-2003.
Li J, Meng X, Deng J, Lu D, Zhang X, Chen Y, Zhu J, Fan A, Ding D, Kong D, Wang Z, Zhao Y. Multifunctional micelles dually responsive to hypoxia and singlet oxygen: enhanced photodynamic therapy via interactively triggered photosensitizer delivery. ACS Appl Mater Interfaces, 2018, 10(20): 17117–17128.
Tao R, Gao M, Liu F, Guo X, Fan A, Ding D, Kong D, Wang Z, Zhao Y. Alleviating the liver toxicity of chemotherapy via pH-responsive hepatoprotective prodrug micelles. ACS Appl Mater Interfaces, 2018, 10(26): 21836–21846.
Meng X, Gao M, Deng J, Lu D, Fan A, Ding D, Kong D, Wang Z, Zhao Y. Self-immolative micellar drug delivery: the linker matters. Nano Res, 2018, 11(12), 6177–6189.
Gao M, Meng X, Guo X, Zhu J, Fan A, Wang Z, Zhao Y. All-active anti-tumor micelles via triggered lipid peroxidation. J Control Release, 2018, 286: 381-393.
Li X, Gao M, Xin K, Zhang L, Ding D, Kong D, Wang Z, Shi Y, Kiessling F, Lammers T, Cheng J, Zhao Y. Singlet oxygen-responsive micelles for enhanced photodynamic therapy. J Control Release. 2017, 260:12-21.
Xin K, Li M, Lu D, Meng X, Deng J, Kong D, Ding D, Wang Z, Zhao Y. Bioinspired coordination micelles integrating high stability, triggered cargo release, and magnetic resonance imaging. ACS Appl Mater Interfaces. 2017, 9(1):80-91.
Liu S, Lu D, Wang X, Ding D, Kong D, Wang Z, Zhao Y. Topology dictates function: Controlled ROS production and mitochondria accumulation via curved carbon materials. J Mater Chem B, 2017, 5: 4918-4925.
Gao M, Deng J, Chu H, Tang Y, Wang Z, Zhao Y, Li G. Stereoselective stabilization of polymeric vitamin E conjugate micelles. Biomacromolecules. 2017, 18(12): 4349–4356.
ResearcherID Publications
Year Title Author(s) Source Volume
2017 Controlled ROS production by corannulene: the vehicle makes a difference Zhang, Limei; Dong, Xiaopeng; Lu, Di; et al. Biomaterials Science 5
2017 Bioinspired Coordination Micelles Integrating High Stability, Triggered Cargo Release, and Magnetic Resonance Imaging Xin, Keting; Li, Man; Lu, Di; et al. ACS Applied Materials & Interfaces 9
2018 Polymeric micelles for pH-responsive lutein delivery Zhang, Dongxue; Wang, Lina; Zhang, Xin; et al. Journal of Drug Delivery Science and Technology 45
2018 Photo-triggered micelles: simultaneous activation and release of microtubule inhibitors for on-demand chemotherapy Chen, Chao; Zhao, Jie; Gao, Min; et al. Biomaterials Science 6
2018 Pharmaceutical micelles featured with singlet oxygen-responsive cargo release and mitochondrial targeting for enhanced photodynamic therapy Zhang, Xin; Yan, Qi; Mulatihan, Di Naer; et al. Nanotechnology 29
2018 Mechanistic insight into the singlet oxygen-triggered expansion of hypoxia-responsive polymeric micelles. Wang, Lina; Huang, Xiaoli; Wang, Bingbing; et al. Biomaterials science 6
2018 In Situ Probing Intracellular Drug Release from Redox-Responsive Micelles by United FRET and AIE. Wang, Xuelin; Li, Juanjuan; Yan, Qi; et al. Macromolecular bioscience 18
2018 In Situ Probing Intracellular Drug Release from Redox-Responsive Micelles by United FRET and AIE Wang, Xuelin; Li, Juanjuan; Yan, Qi; et al. Macromolecular Bioscience 18
2018 Imidazole-Bearing Polymeric Micelles for Enhanced Cellular Uptake, Rapid Endosomal Escape, and On-demand Cargo Release Lu, Di; An, Yang; Feng, Simin; et al. Aaps Pharmscitech 19
2018 Hierarchical theranostic nanomedicine: MRI contrast agents as a physical vehicle anchor for high drug loading and triggered on-demand delivery Liu, Guangqin; Deng, Jian; Liu, Fang; et al. Journal of Materials Chemistry B 6