Home / People / Faculty / Yanjun Zhao

Yanjun Zhao ——Professor

Nationality:
CHINA
Phone:
022-27407882
Email:
zhaoyj@tju.edu.cn
Office:
Room 412-1, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2005-2010 Ph. D. Pharmacy King’s College London, UK
2002-2005 M.S. Biochemical Engineering Dalian Institute of Chemical Physics, CAS
1998-2002 Bachelor Polymer Dalian University of Technology
Professional Experience
2009-2009 Research Scientist MedPharm Ltd. (UK)
2010-2012 Lecturer Tianjin University, China
2012-2018 Associate Professor Tianjin University, China
2018- Professor Tianjin University, China
Research Area

The research in the group of Zhao encompasses four main areas, including (1) Stimuli-responsive drug delivery systems; (2) Ferroptosis-targeting nanomedicines; (3) Photo-triggered microtubule inhibitors; (4) Pharmaceutical micelles, biomaterials and nanomaterials.

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Honors and Awards
2013: Tianjin University “Elite Scholar”
2009: Chinese Government Award for Outstanding Self-financed Students Abroad
2005: Dorothy Hodgkin Postgraduate Awards
Patents
CN Patent: ZL 2013 1 0755965.7
CN Patent: ZL 2014 1 0008911.9
Highlighted Publications
Deng J, Liu F, Wang L, An Y, Gao M, Wang Z, Zhao Y. Hypoxia- and singlet oxygen-responsive chemo-photodynamic micelles featured with glutathione depletion and aldehyde production. Biomater Sci, 2019, 7(1):429-441.
Liu G, Deng J, Liu F, Wang Z, Peer D, Zhao Y. Hierarchically theranostic nanomedicine: MRI contrast agents as the physical vehicle anchor for high drug loading and triggered on-demand delivery. J Mater Chem B, 2018, 6(13): 1995-2003.
Li J, Meng X, Deng J, Lu D, Zhang X, Chen Y, Zhu J, Fan A, Ding D, Kong D, Wang Z, Zhao Y. Multifunctional micelles dually responsive to hypoxia and singlet oxygen: enhanced photodynamic therapy via interactively triggered photosensitizer delivery. ACS Appl Mater Interfaces, 2018, 10(20): 17117–17128.
Tao R, Gao M, Liu F, Guo X, Fan A, Ding D, Kong D, Wang Z, Zhao Y. Alleviating the liver toxicity of chemotherapy via pH-responsive hepatoprotective prodrug micelles. ACS Appl Mater Interfaces, 2018, 10(26): 21836–21846.
Meng X, Gao M, Deng J, Lu D, Fan A, Ding D, Kong D, Wang Z, Zhao Y. Self-immolative micellar drug delivery: the linker matters. Nano Res, 2018, 11(12), 6177–6189.
Gao M, Meng X, Guo X, Zhu J, Fan A, Wang Z, Zhao Y. All-active anti-tumor micelles via triggered lipid peroxidation. J Control Release, 2018, 286: 381-393.
Li X, Gao M, Xin K, Zhang L, Ding D, Kong D, Wang Z, Shi Y, Kiessling F, Lammers T, Cheng J, Zhao Y. Singlet oxygen-responsive micelles for enhanced photodynamic therapy. J Control Release. 2017, 260:12-21.
Xin K, Li M, Lu D, Meng X, Deng J, Kong D, Ding D, Wang Z, Zhao Y. Bioinspired coordination micelles integrating high stability, triggered cargo release, and magnetic resonance imaging. ACS Appl Mater Interfaces. 2017, 9(1):80-91.
Liu S, Lu D, Wang X, Ding D, Kong D, Wang Z, Zhao Y. Topology dictates function: Controlled ROS production and mitochondria accumulation via curved carbon materials. J Mater Chem B, 2017, 5: 4918-4925.
Gao M, Deng J, Chu H, Tang Y, Wang Z, Zhao Y, Li G. Stereoselective stabilization of polymeric vitamin E conjugate micelles. Biomacromolecules. 2017, 18(12): 4349–4356.
ResearcherID Publications
Year Title Author(s) Source Volume
2014 Label-free chemiluminescent ATP aptasensor based on graphene oxide and an instantaneous derivatization of guanine bases Song, Yinhuan; Yang, Xu; Li, Ziqi; et al. Biosensors and Bioelectronics 51
2014 Interplay of stimuli-responsiveness, drug loading and release for a surface-engineered dendrimer delivery system Liu, Ruihong; Sun, Mingjing; Liu, Xipan; et al. International Journal of Pharmaceutics 462
2014 Acid-Responsive Polymeric Nanocarriers for Topical Adapalene Delivery Guo, Chenchen; Khengar, RajeshreeH; Sun, Mingjing; et al. Pharmaceutical Research
2014 Dendritic nanoconjugate containing optimum folic acid for targeted intracellular curcumin delivery Fu, Yunlan; Gao, Xuli; Wan, Ying; et al. RSC Advances 4
2014 A cascade amplification strategy based on rolling circle amplification and hydroxylamine amplified gold nanoparticles enables chemiluminescence detection of adenosine triphosphate Wang, Ping; Zhang, Tonghuan; Yang, Taoyi; et al. Analyst 139
2015 Tuning the architecture of polymeric conjugate to mediate intracellular delivery of pleiotropic curcumin Wang, Zheng; Chen, Chao; Zhang, Qi; et al. European Journal of Pharmaceutics and Biopharmaceutics 90
2015 Triggered-release polymeric conjugate micelles for on-demand intracellular drug delivery Cao, Yanwu; Gao, Min; Chen, Chao; et al. Nanotechnology 26
2015 Residue cytotoxicity of a hydrazone-linked polymer-drug conjugate: implication for acid-responsive micellar drug delivery Zhang, Yu; Gao, Min; Chen, Chao; et al. Rsc Advances 5
2015 On-demand combinational delivery of curcumin and doxorubicin via a pH-labile micellar nanocarrier Li, Haoyu; Li, Man; Chen, Chao; et al. International Journal of Pharmaceutics 495
2015 Nitric oxide-releasing graft polymer micelles with distinct pendant amphiphiles Gao, Min; Liu, Sihui; Fan, Aiping; et al. RSC Advances 5