Home / People / Faculty / Jing Wei

Jing Wei——Lecturer

Nationality:
CHINA
Phone:
022-87401830
Email:
betty_wj@tju.edu.cn
Office:
Room A205, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2001-2004 Master of Engineering Pattern Recognition and Intelligence System Tianjin University, CN
2004-2007 Doctor of Engineering Medicinal Chemistry Tianjin University CN
Professional Experience
2007-2015 lecturer Tanjin University , China
1995-2001 Physician Laboratorian of Center for Disease Control and Prevention, Hexi District, Tianjin
Research Area

Wei’s research addresses mechanisms of drug activity with associated drug design.  Computational approaches (e.g., molecular docking, pharmacophore modeling, quantitative structure-activity relationship (QSAR), molecular dynamics) are used to identify and characterize putative ligand binding sites, elucidate binding mechanisms, and guide rational design of potentially new drugs.

Honors and Awards
魏静,四乙酰核糖和二乙酰阿昔洛韦合成的新工艺,天津市人民政府,科技进步奖,二等奖,2009。(赵康、陈维瑜、魏静、杜云飞、王松青、苏艳芳、张秀东、陈炎泉)
魏静,第十三届“挑战杯”天津市大学生课外学术科技作品竞赛优秀指导教师,天津市委员会、天津市科学技术委员会、天津市教育工作委员会等,2015。
Patents
Highlighted Publications
The comparison of BLyS-binding peptides from phage display library and computer-aided design on BLyS–TACI interaction. Int. Immunopharmacol. 2015, 24 (2) 219–223.
Computer-aided de novo ligand design and docking/molecular dynamics study of Vitamin D receptor agonists. J. Mol. Model., 2012, 18(1): 203–212.
Docking and molecular dynamics study on the inhibitory activity of novel inhibitors on epidermal growth factor receptor (EGFR). Med Chem. 2011, 7(1):24-31.
Adevances in the study of A2B adenosine receptor antagonists. Anta Pharmaceutica Sinica,2008,43 (3): 241-246.
ResearcherID Publications
Year Title Author(s) Source Volume
2016 Mechanistic Study of Human Glucose Transport Mediated by GLUT1 Fu, Xuegang; Zhang, Gang; Liu, Ran; et al. Journal of Chemical Information and Modeling 56
2016 A Novel BLyS Peptibody Down-Regulates B Cell and T Helper Cell Subsets In Vivo and Ameliorates Collagen-Induced Arthritis Zhu, Weiwei; Sun, Xiaolin; Zhu, Lei; et al. Inflammation 39
2016 A Comparison of Biological Activity of B Lymphocyte Stimulator (BLyS) Antagonist Peptibodies and the Elucidation of Possible BLyS Binding Sites Hao, Xiafei; Zhu, Yanfeng; Zheng, Chang; et al. Protein and Peptide Letters 23
2017 Selective Binding BAFF/APRIL by the In and Outside Conservative Region of BCMA Zheng, Chang; Zhang, Xiaojuan; Zhao, Zhen; et al. Protein and Peptide Letters 24
2017 N6-Isopentenyladenosine promoted HeLa cell apoptosis through inhibitions of AKT and transforming growth factor beta-activated kinase 1 activation. Li, Miao; Qi, Yonghao; Wei, Jing; et al. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 39
2017 Molecular mechanism of the selectivity between BAFF/APRIL and their receptors by molecular simulations Fu, Xuegang; Mao, Zhuo; Li, Siming; et al. Molecular Simulation 43
2017 Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6 Qi, Yonghao; Pradipta, Ambara R.; Li, Miao; et al. Journal of Experimental & Clinical Cancer Research 36
2017 A novel antioxidant and ACE inhibitory peptide from rice bran protein: Biochemical characterization and molecular docking study Wang, Xiuming; Chen, Haixia; Fu, Xuegang; et al. Lwt-Food Science and Technology 75
2011 Identification of ligand binding site on RXR gamma using molecular docking and dynamics methods Zhao, Peng; Liao, Qing-hua; Ren, Cheng-Feng; et al. Journal of Molecular Modeling 17
2011 Molecular docking and pharmacophore model studies of Rho kinase inhibitors Wang, Dong-Hua; Qu, Wan-Lu; Shi, Liu-Qing; et al. Molecular Simulation 37
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