Home / People / Faculty / Yunfei Du

Yunfei Du ——Professor

Nationality:
CHINA
Phone:
022-27406121
Email:
duyunfeier@tju.edu.cn
Office:
Room A208, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2007 Ph. D. Tianjin University, CN
Professional Experience
2007-2009 Assistant Professor Tianjin University.
2009-2013 Associate Professor Tianjin University
2012-2019 Associate Dean / Party Vice-Secretary Tianjin University
2013-2019 Professor Tianjin University
2019- Associate Dean Tianjin U
Research Area

The research area of the Du group involves investigation of hypervalent iodine (III) – mediated transformations, including oxidative coupling, rearrangement, cascade reactions, and asymmetric reactions.  Additionally, the group develops metal-free methodology for the constructionof heterocyclic compounds and pharmaceutical agents.

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Honors and Awards
四乙酰核糖和二乙酰阿昔洛韦合成的新工艺,天津市人民政府,科技进步奖,二等奖,2010。(赵康、陈维瑜、魏静、杜云飞、王松青、苏艳芳、张秀东、陈炎泉)
第十二届“挑战杯”天津市大学生课外学术科技作品竞赛优秀指导教师,天津市委员会、天津市科学技术委员会、天津市教育工作委员会等,优秀指导教师,2013。(杜云飞)
天津大学“北洋青年学者”,2015年。
天津市“131”创新型人才培养工程第一层次人选,2016年。
Patents
杜云飞,袁玉成,赵康,一种通过C–N氧化偶联合成取代二氨基烯烃衍生物的方 法,中国,2014104793464
杜云飞,程然,赵康,一种通过环合消除一锅法合成4(3H)-喹唑啉酮衍生物的 方法,中国,201410113565.0。
杜云飞,程然,赵康,一种通过环合消除一锅法合成4(3H)-喹唑啉酮衍生物的 方法,中国,201410113565.0。
杜云飞,尚巳耘,赵康,一种合成二苯并二氢-1,3-二氮杂䓬类衍生物的方法, 中国,201310608894.8。
杜云飞,吕晶磊,赵康,一种2-吲哚酮-3-羧酸酯类衍生物的合成方法,中国,2 01310503250.2。
杜云飞,李旭明,张翔,赵康,一种二苯西平类衍生物的合成方法,中国,2013 10455049.1。
杜云飞,吕晶磊,尚巳耘,赵康,一种四氢-γ-咔啉类衍生物的合成方法,中 国,201310022038.4。
杜云飞,刘乐,贺巧巧,赵康,1,3-二腈基2-取代-1H-茚类衍生物及其制备方 法,中国,201210044059.1。
杜云飞,赵康,赵菲菲,刘昕,齐蕊,2-三氟甲基噁唑类衍生物的合成方法, 中国,201110120698.7。
杜云飞,云希柳,毕文英,赵康,一种氮取代四氢咔唑酮衍生物的制备新方法 ,中国,201010252043.0。
祁秀香,杜云飞,闫俏,赵康,李慧,合成N-芳基吲哚-3-腈衍生物的方法,中 国,201010560853.2。
杜云飞,汤丽娜,庞永乐,阎俏,祁秀香,一种合成Coumestan类衍生物的新方 法,中国,201010171129.0。
杜云飞,马辉,赵康,异吲哚啉羧酸酯衍生物的制备方法及其应用,中国,201 010187238.1。
Highlighted Publications
Shang, S.; Zhang-Negrerie, D.; Du, Y.;* Zhao, K.* Intramolecular Metal-free Oxidative Aryl-aryl Coupling: An Unusual Hypervalent Iodine-mediated Rearrangement of 2-Substituted N-Phenylbenzamides. Angew. Chem., Int. Ed. 2014, 53, 6216. (Hot Paper)
Yu, J.; Zhang-Negrerie, D.; Du, Y.* Cu(OAc)2-Mediated Cascade Annulation of Diarylalkyne Sulfonamides through Dual C-N Bond Formation: Synthesis of 5,10-Dihydroindolo[3,2-b]indoles. Org. Lett. 2016, 18, 3322–3325.
Cao, Y.; Zhang, X.; Lin, G.; Zhang-Negrerie, D.; Du, Y.* Chiral Aryliodine-Mediated Enantioselective Organocatalytic Spirocyclization: Synthesis of Spirofurooxindoles via Cascade Oxidative C-O and C-C Bond Formation. Org. Lett. 2016, 18, 5580–5583.
Zhang, B.; Zhang,X.; Hu, B.; Sun, D.; Wang, S.; Zhang-Negrerie, D.; Du. Y.* PhI(OCOCF3)2-Mediated Construction of 2-Spiropseudoindoxyl Skeleton via Cascade Annulation of 2-Sulfonamido-N-phenylpropiolamide Derivatives. Org. Lett. 2017, 19, 902.
Zhao, X.; Li, Q.; Xu, J.; Wang, D.; Zhang-Negrerie, D.; Du, Y.* Cascade Synthesis of Benzothieno[3,2-b]indoles Under Oxidative Conditions Mediated by CuBr and tert-Butyl Hydroperoxide. Org. Lett. 2018, 20, 5933-5937.
ResearcherID Publications
Year Title Author(s) Source Volume
2014 Oxidant- and metal-free synthesis of 4(3H)-quinazolinones from 2-amino-N-methoxybenzamides and aldehydes via acid-promoted cyclocondensation and elimination Cheng, Ran; Tang, Linlin; Guo, Tianjian; et al. Rsc Advances 4
2014 Organocatalytic amination of alkyl ethers via n-Bu4NI/t-BuOOH-mediated intermolecular oxidative C(sp(3))-N bond formation: novel synthesis of hemiaminal ethers Dian, Longyang; Wang, Sisi; Zhang-Negrerie, Daisy; et al. Chemical Communications 50
2014 Metal-Free Tandem Oxidative Aryl Migration and C-C Bond Cleavage: Synthesis of alpha-Ketoamides and Esters from Acrylic Derivatives Liu, Le; Du, Liang; Zhang-Negrerie, Daisy; et al. Organic Letters 16
2014 Metal-Free Synthesis of 2-Oxindoles via PhI(OAc)(2)-Mediated Oxidative C-C Bond Formation Lv, Jinglei; Zhang-Negrerie, Daisy; Deng, Jun; et al. Journal of Organic Chemistry 79
2014 Intramolecular Metal-Free Oxidative Aryl-Aryl Coupling: An Unusual Hypervalent-Iodine-Mediated Rearrangement of 2-Substituted N-Phenylbenzamides Shang, Siyun; Zhang-Negrerie, Daisy; Du, Yunfei; et al. Angewandte Chemie-International Edition 53
2014 Hypervalent Iodine-Mediated Oxygenation of N,N-Diaryl Tertiary Amines: Intramolecular Functionalization of sp(3) C-H Bonds Adjacent to Nitrogen Zhang, Ningning; Cheng, Ran; Zhang-Negrerie, Daisy; et al. Journal of Organic Chemistry 79
2014 Direct Oxidative Coupling of Enamines and Electron-Deficient Amines: TBAI/TBHP-Mediated Synthesis of Substituted Diaminoalkenes under Metal-Free Conditions Yuan, Yucheng; Hou, Wenjuan; Zhang-Negrerie, Daisy; et al. Organic Letters 16
2014 Construction of 1,4-Benzodiazepine Skeleton from 2-(Arylamino)benzamides through Phl(OAc)(2)-Mediated Oxidative C-N Bond Formation Li, Xuming; Yang, Liu; Zhang, Xiang; et al. Journal of Organic Chemistry 79
2015 Synthesis of Chromeno[2,3-b]indol-11(6H)-one via PhI(OAc)(2)-Mediated Intramolecular Oxidative C(sp(2))-N(H-2) Bond Formation Sun, Jiyun; Zhang-Negrerie, Daisy; Du, Yunfei; et al. Journal of Organic Chemistry 80
2015 PhI(OCOCF3)(2)-Mediated Cyclization of o-(1-Alkynyl)benzamides: Metal-Free Synthesis of 3-Hydroxy-2,3-dihydroisoquinoline-1,4-dione Yang, Chao; Zhang, Xiang; Zhang-Negrerie, Daisy; et al. Journal of Organic Chemistry 80