Home / People / / Xuedong Yang

Xuedong Yang ——Associate Professor

Nationality:
CHINA
Phone:
022-87401152
Email:
yangxd@tju.edu.cn
Office:
Room A504, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2001 Ph. D. Chin. Acad. of Med. Sci./Peking Un. Med. College,
2002 Postdoctoral Tsinghua University, CN
Professional Experience
Research Area

The research in the group of Yang involves the fields of natural products, medicinal chemistry and biochemistry research focused at the discovery and development of bioactive natural products and their analogs as clinical trials drug candidates.  Work is carried out to understand the relationship between bioactive constituents and therapeutic effects of traditional Chinese medicine. Using basic natural products and medicinal chemistry principles coupled with modern technologies, including new analytical techniques, computational techniques, and mechanism of action or target-based medicinal chemistry research evaluation methods, the group works towards discovery and development of potential therapeutic drugs and functional foods.

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Honors and Awards
Patents
Highlighted Publications
Zhu, C.; Jing, L.; Yu, N.; Yang, X.; Zhao, Y. A new lignan and active compounds inhibiting NF-kB signaling pathway from Caulis trachelospermi. Acta Pharmaceut. Sin. B 2013, 3, 109.
Li, D.; Fedeles, B. I.; Shrivastav, N.; Delaney, J. C.; Yang, X.; Wong, C.; Drennan, C. L.; John M. Essigmann, J. M. Removal of N-Alkyl Modifications from N2-Alkylguanine and N4-Alkylcytosine in DNA by the Adaptive Response Protein AlkB. Chem. Res. Toxicol. 2013, 26, 1182.
Li, D.; Delaney, J. C.; Page, C. M.; Yang, X.; Chen, A. S.; Wong, C.; Drennan, C. L.; Essigmann, J. M. Exocyclic Carbons Adjacent to the N6 of Adenine are Targets for Oxidation by the Escherichia coli Adaptive Response Protein AlkB. J. Am. Chem. Soc. 2012, 134, 8896.
Yang, X.-D.; Tang, X.-Y.; Sang, L. Rapid identification of micro-constituents in monoammonium glycyrrhizinate raw materials by high-pressure solid phase extraction-high performance liquid chromatography-mass spectrometry. China J. Chin. Materia. Medica 2012, 37, 3416.
Yang, X.-D.; Wu, X.; Hu, L.-C.; Guo, H.-N. Effect of different solvents on extraction of effective components from Ligusticum chuanxiong. China J. Chin. Materia. Medica 2012, 37, 1942.
ResearcherID Publications
Year Title Author(s) Source Volume