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Benjamin Clark——Associate Professor

Nationality:
New Zealand
Phone:
022-27404021
Email:
bclark@tju.edu.cn
Office:
Room 505, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2001-2006 Ph. D. Chemistry Brisbane, Australia
1997-2000 B.Sc. Chemistry and Biochemistry Victoria University of Wellington, NZ
Professional Experience
2006-2007 Postdoctoral Researcher UC San Diego, USA
2007-2010 Postdoctoral Researcher University College Dublin, Ireland
2011-2015 Postdoctoral Researcher University of Hawai’i at Hilo, USA
Research Area

Research in the Clark group focuses on microbial natural products as applied to drug discovery, metabolomics, and chemical ecology. Microbes have long been a source of potent antimicrobial and anticancer agents, and we have a particular interest in marine and extremophilic microbes as a source of new drug leads. We also investigate chemical ecology: what role the metabolites serve for the microbe itself, and how are they involved in the interaction of microbes with other organisms. The group uses metabolic profiling and multivariate statistical techniques in all of these research avenues in order to classify samples, identify active components, and elucidate the interactions of molecules and organisms. While microbes are the primary focus of the group we also have experience working with plants and marine organisms if there are particularly interesting ecological questions to be addressed in these areas. 


Honors and Awards
Embark Postdoctoral Fellowship - Irish Research Council for Science, Engineering and Technology (2007-2009)
President’s Award: Travel Grant – University College Dublin (2008)
Patents
Highlighted Publications
Clark, Benjamin R.; Engene, Niclas; Teasdale, Margaret E.; Rowley, David C.; Matainaho, Teatulohi; Valeriote, Frederick A.; Gerwick, William H. Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum. J. Nat. Prod. 2008, 71, 1530-1537.
Clark, Benjamin R.; Murphy, Cormac D. Biosynthesis of pyrrolylpolyenes in Auxarthron umbrinum. Org. Biomol. Chem. 2009, 7, 111-116.
Fukuda, Takashi; Miller, Eric D.; Clark, Benjamin R.; Alnauman, Ali; Murphy, Cormac D.; Jensen, Paul R.; Fenical, William. Structures and biosynthesis of the pyridinopyrones, new polyenepyrones from a marine-derived Streptomyces strain. J. Nat. Prod. 2011, 74, 1773–1778.
Clark, Benjamin R.; O’Connor, Stephen; Fox, Deirdre; Leroy, Jacques; Murphy, Cormac D. Production of anticancer polyenes through precursor-directed biosynthesis. Org. Biomol. Chem. 2011, 9, 6306-6311.
Clark, Benjamin R.; Bliss, Barbara J.; Suzuki, Jon Y.; Borris, Robert P. Chemotaxonomy of Hawaiian Anthurium cultivars based on multivariate analysis of phenolic metabolites. J. Agric. Food Chem. 2014, 62, 11323-11334.
ResearcherID Publications
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