Home / People / / Zefang Wang

Zefang Wang——Associate Professor

Nationality:
China
Phone:
Email:
zefangwang@tju.edu.cn
Office:
Room 328, School of Life Sciences (No. 15 building) , Tianjin Universtiy
School:
School of Life Sciences
ResearcherID:
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Education Experience
2000-2004 Bachelor of Science Bioengineering Tianjin University of Science and Technology
2005-2010 Ph. D. Microbiology Nankai University
2008-2009 Ph. D. Protein Engineering VTT Technical Research Centre of Finland
2010-2014 Postdoctoral Cell Biology New York University
Professional Experience
2004-2016 Tianjin University
Research Area

My research is focused on two specific areas, one is hydrophobin and another one is biology and disease of urothelium. For the hydrophobin study, my research is involved but not limited to: 1) Study protein-protein interaction and protein assembly in vitro and in vivo. 2) Protein expression, purification and characterization in both prokaryotic and eukaryotic systems.  3) Hydrophobin based drug and gene delivery systems. 4) Hydrophobin based chip and sensors. 5) Antibody production and purification. 6) Large-scale high-density fermentation and downstream separation. For the urothelium study, my research is involved but not limited to: 1) Study the urothelial disease like bacterial urinary tract infection and bladder. 2) study of ATP release channel of urothelium in mouse model. 3) Drug release and delivery by adenovirus and liposome in urothelium. 4) Characterization and function study of lipid raft proteins. 5) Study the stem cell of the urothelium.

 


Honors and Awards
Gold award for international genetically engineered machine competition (2015, Instructor)
Best new basic part for international genetically engineered machine competition (2015, Instructor)
Best new application project for international genetically engineered machine competition (2015, Instructor)
Excellent doctor degree dissertation in Nankai University (2010).
Excellent doctoral graduate in Nankai University (2010).
First price for graduate student academic section in Nankai University (2010).
Chinese government scholarship for outstanding doctoral students (2008).
Patents
L. Yu, Z.F. Wang, S.R. Feng, H.J. Xu, Q. Zhang, M.Q. Qiao, Application of fungal hydrophobins to biochips. Chinese National Invention Patent (No: 101216485).
Z.F. Wang, S.R. Feng, Y.J. Huang, H.J. Xu, Q. Zhang, H. Feng, M.Q. Qiao, Method of ultrafiltration to produce Class II hydrophobin HFBI. Chinese National Invention Patent (No: 101215321).
Highlighted Publications
Z.F. Wang, S.R. Feng, Y.J. Huang, H.J. Xu, M.Q. Qiao, Prokaryotic expression, purification and polyclonal antibody production of a hydrophobin from Grifola Frondosa. 2010, Acta Biochimica et Biophysica Sinica, 42, 388-395.
Z.F. Wang, S.R. Feng, Y.J. Huang, H.J. Xu, M.Q. Qiao, Expression and characterization of a Grifola frondosa hydrophobin in Pichia pastoris. 2010, Protein Expression and Purification, 72, 19-25.
Z.F. Wang, M. Lienemann, M.Q. Qiao, M.L. Linder. Mechanisms of protein adhesion on surface films of hydrophobin. 2010, Langmuir, 26, 8491-8496.
Z.F. Wang, Y.Y. Wang, Y.J. Huang, S. Li,S.R. Feng, H.J. Xu, M.Q. Qiao, Characterization and application of hydrophobin-dispersed multi-walled carbon nanotubes. 2010, Carbon, 48, 2890-2898.
Z.F. Wang, Y.J. Huang, S. Li, H.J. Xu, M.Q. Qiao, M.L. Linder. Hydrophilic modification of polystyrene with hydrophobin for time-resolved immunofluorometric assay. 2010, Biosensors and Bioelectronics, 26, 1074-1079.
ResearcherID Publications
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