Home / People / / Hyun Min Kim

Hyun Min Kim——Associate Professor

Republic of Korea
HKim @ tju. edu. cn
Building 24 Lab 413
School of Pharmaceutical Science and Technology
Group weblink
Education Experience
2009-2016 Postdoctoral Genetics Harvard Medical School, U.S.A
2003-2009 Ph. D. Molecular Genetics Georgia Institude of Technology, U.S.A
1997-1999 M.S. Microbiology Hanyang University, S. Korea
Professional Experience
2009-2016 Research fellow Harvard Medical School, U.S.A
2004-2009 Research and Teaching assistant Georgia Institute of Technology, U.S.A
1999-2003 Research scientist Hanyang University Medical School, S.Korea
1997-1998 Research and Teaching assistant Hanyang University, S.Korea
Research Area


We are interested in understanding the DNA repair mechanism in the germline. Especially, we have focused on investigating the epigenetic regulation of DNA damage response and repair. We use a microscopic size nematode C. elegans and mammalian cells to study epigenetic control of DNA repair mechanism. 1. The role of conserved Epigenetic regulators in DNA repair and damage response. 2.The role of novel and conserved gene of DNA repair and damage response.    

We are recuiting hard working studentsStudents interested in working in Genetics or Molecular biology in my lab, send an E-mail to KimTju@qq.com and visit my lab. Lab website at  http://KimLab.website2.me/

Honors and Awards
Scholarship from Keystone Symposia on Molecular and Cellular Biology, March 1 2009.
Travel award from graduate research mentor for Undergraduate Research Scholar, Georgia Tech/Emory Center for the Engineering of Living Tissue, 2009.
Sarstedt® Graduate Student Award for ‘Outstanding Accomplishments in Ph.D. research’, Dec 11 2008, Sandi Battista, Sarstedt, Inc.
Travel award from research mentor for Research Experience for Undergraduates 2007-2008.
Outstanding research paper of year 2001, Dec 2001, Chung-Ram association, Korea.
Graduate tuition scholarship, Hanyang University, 1998.
Undergraduate tuition scholarship, Hanyang University, 1994.
Highlighted Publications
Hyun-Min Kim, Sara Beese-Sims and Monica Colaiácovo: Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 are required for maintaining histone methylation levels and interact with the histone demethylase LSD1/SPR-5 in C. elegans. GENETICS/2018/300823R1. # Highlighted paper by Genetics Society of America.2018 June.
Nuria Ferrandiz, Consuelo Barroso, Oana Telecan, Hyun-Min Kim, Sarah Testori, Peter Faull, Pedro Cutillas, Bram Snijders, Monica P. Colaiacovo and Enrique Martinez-Perez: Spatiotemporal regulation of Aurora B recruitment ensures two-step release of cohesion during meiosis. Nature Communications. 2018 Feb 26;9(1):834. doi: 10.1038/s41467-018-03229-5.
Nottke AC, Kim HM, Colaiácovo MP. Wrestling with Chromosomes: The Roles of SUMO During Meiosis. Adv Exp Med Biol. 2017;963:185-196. doi: 10.1007/978-3-319-50044-7_11.
Gao J, Barroso C, Zhang P, Kim HM, Li S, Labrador L, Lightfoot J, Gerashchenko MV, Labunskyy VM, Dong MQ, Martinez-Perez E, Colaiácovo MP. N-terminal acetylation promotes synaptonemal complex assembly in C. Elegans. Genes & Development 30(21):2404-2416 • November 2016
Kim HM and Colaiácovo MP. CRISPR-Cas9-guided Genome Engineering in C. elegans. Current Protocols in Molecular Biology, 2016 July. http://onlinelibrary.wiley.com/doi/10.1002/cpmb.7/full
Norris AD*, Kim HM*, Colaiácovo MP and Calarco JA. Efficient Genome Editing in Caenorhabditis elegans with a Toolkit of Dual Marker Selection Cassettes. 2015 Aug. GENETICS. (*Co-first author)
Kim HM# and Colaiácovo MP#. DNA damage sensitivity assays in Caenorhabditis elegans. Bio-protocol (ISSN: 2331-8325), 2015 Mar. (#Co-correspondence)
Gao J, Kim HM, Elia AE, Elledge SJ, Colaiácovo MP. NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking Acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis. PLOS Genet, 2015 Mar11(3):e1005029.
Kim HM and Colaiácovo MP. New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans. GENETICS. 2015 Jun;200(2):495-504.
Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaiácovo MP, Yankner BA. ‘REST and stress resistance in ageing and Alzheimer's disease’, Nature, 2014 Mar 27;507(7493):448-54.
Saito TT, Lui DY, Kim HM, Meyer K, Colaiácovo MP. ‘Interplay between Structure-Specific Endonucleases for Crossover Control during Caenorhabditis elegans Meiosis’, PLOS Genet, 2013 Jul;9(7):e1003586.
Sengupta MS, Low WY, Patterson JR, Kim HM, Traven A, Beilharz TH, Colaiacovo MP, Schisa JA and Boag PR, 'ifet-1 is a broad scale translational repressor required for normal P granule formation in C. elegans', J Cell Sci, 2013 Feb 1;126(Pt3):850-9.
Waisertreiger IS, Liston VG, Menezes MR, Kim HM, Lobachev KS, Stepchenkova EI, Tahirov TH, Rogozin IB and Pavlov YI,'Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools', Environ Mol Mutagen, Oct 2012, vol.53, pp.699-724.
Tang W, Dominska M, Greenwell PW, Harvanek Z, Lobachev KS, Kim HM, Narayanan V, Mirkin SM and Petes TD, 'Friedreich's ataxia (GAA)n(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae', PLOS Genet, Jan 2011, vol.7, pp.e1001270
Kim HM, Narayanan V, Mieczkowski PA, Petes TD, Krasilnikova MM, Mirkin SM and Lobachev KS, 'Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair', EMBO Journal, Nov 2008, vol.27,pp.2896-906
Narayanan V, Mieczkowski PA, Kim HM, Petes TD and Lobachev KS, 'The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks', Cell, Jun 2006, vol.125, pp.1283-96
Kim HM, Ohn TB, Min BR and Choi YK, 'Sequence analysis and insertional inactivation of a gene encoding Moraxella sp. CK-1 cell wall hydrolase', Antonie Van Leeuwenhoek, June 2001, vol.79, pp.163-71
ResearcherID Publications
Year Title Author(s) Source Volume