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Imran Ahmd Khan——

Lab 512, Building No. 24, School of Pharmaceutical Sciences and technology
School of Pharmaceutical Science and Technology
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Education Experience
2005-2007 Master of Science Chemistry Delhi University
2009-2014 Ph. D. Medicinal Chemistry Central Drug Research Institute, INDIA
2014-2016 Postdoctoral Synthetic Chemistry Guru Nanak Dev University, INDIA
Professional Experience
2007-2009 (i) Junior Research Fellow at Central Drug Researc
2009-2012 (ii) Senior Research Fellow at Central Drug Resear
2012-2013 (iii) Assistant Manager (Research & Developmen
2013-2014 (iv) Technical Officer at Global Institute of Phar
2014-2014 (v) Guest Faculty, Babasaheb Bhimrao Ambedkar Univ
2014-2016 (vi) Dr. D. S. Kothari Postdoctoral Fellow Guru Na
2016-2017 Post-doctoral, Tianjin University
Research Area

Synthetic Organic Chemistry

Natural product synthesis



Honors and Awards
Dr. D.S. Kothari Post-Doctoral fellowship (UGC-DSKPDF-2014)
two Incentives awards for publications in Advance synthesis and Catalysis from CDRI in the year 2013
Highlighted Publications
Imran A. Khan, Anil K. Saxena, Parikh–Doering oxidation–dehydration–Ugi cyclization cascade in the development of lactams from formidoalkanols (3>chain length>7), Tetrahedron, 2012, 68, 294-299. (DOI: 10.1016/j.tet.2011.10.050)
Imran A. Khan, Anil K. Saxena, Employing lactams for the unprecedented enantiopure synthesis of non-natural amino acid derivatives, Tetrahedron, 2012, 68, 1272-1279. (DOI: 10.1016/j.tet.2011.11.047)
Vishal M. Balaramnavar, Imran A. Khan, Jawed Akhtar Siddiqui, Mohd Parvez Khan, Bandana Chakravarti, Kunal Sharan, Gaurav Swarnkar, Namrata Rastogi, H. H. Siddiqui, Durga Prasad Mishra, Naibedya Chattopadhyay, and Anil K. Saxena. Identification of Novel 2-((1-(Benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)benzoic Acid Analogues as BMP-2 Stimulators. Journal of Medicinal Chemistry, 2012, 55, 8248–8259. (DOI: 10.1021/jm300985d)
Imran A. Khan, Vishal M. Balaramnavar, Anil K. Saxena, Identification and optimization of novel pyrimido-isoxazolidine and oxazine as selective hydride donors, Tetrahedron, 2012, 68, 10122-10129. (DOI: 10.1016/j.tet.2012.09.105)
Sugandha Sharma, Imran A. Khan and Anil K. Saxena. Room Temperature Palladium-Catalyzed Decarboxylative Acyl/Aroylation using [Fe(III)(EDTA)(η2-O2)]3− as Oxidant at Biological pH. Advance Synthesis and Catalysis, 2013, 355, 673-678. ( DOI: 10.1002/adsc.201201085)
Imran A. Khan and Anil K. Saxena. (R/S)-BINOL-α-phosphoryloxy enecarbamate mediated and (R/S)-Ti (IV)- Binolates catalyzed Enantioselective intramolecular Heck/Aza–Diels–Alder cycloaddition (IHADA): An Expedient Methodology. Advance Synthesis and Catalysis, 2013, 355, 2617–2626. (DOI: 10.1002/adsc.201300522)
Imran A. Khan and Anil K. Saxena. A Metal free, Mild, Non-Epimerizing, Chemo- and Enantio-/or Diastereoselective N-Alkylation of amines by alcohols via Oxidation/Imine-Iminium formation/Reductive Amination: A Pragmatic Synthesis of Octahydropyrazinopyridoindoles and higher ring analogues. The Journal of Organic Chemistry, 2013, 78, 11656–11669. (DOI: 10.1021/jo4012249)
Chandra S. Azad, Vishal M. Balaramnavar, Imran A. Khan, Pawan K. Doharey, Jitendra K. Saxena and Anil K. Saxena. Operative conversions of 3-carboxy-4-quinolones into 3-nitro-4-quinolones via ipso-nitration: potential antifilarial agents as inhibitors of Brugia malayi thymidylate kinase. RSC Advances, 2015, 5, 82208-82214. (DOI: 10.1039/C5RA18036H)
Shahi I. Reja, Imran A. Khan, Vandana Bhalla and Manoj Kumar. A TICT based NIR-fluorescent probe for human serum albumin: a pre-clinical diagnosis in blood serum. Chemical Communication, 2016, 52, 1182-1185. (DOI: 10.1039/C5CC08217J)
Shome S. Bhunia, Ankita Misra, Imran A. Khan, Stuti Gaur, Manish Jain, Surendra Singh, Aaruni Saxena, Thomas Hohlfield, Madhu Dikshit, and Anil K. Saxena. Novel Glycoprotein VI Antagonists as Antithrombotics: Synthesis, Biological Evaluation, and Molecular Modeling Studies on 2,3-Disubstituted Tetrahydropyrido(3,4-b)indoles, Journal of Medicinal Chemistry, 2017, 60: 322-37. (DOI: 10.1021/acs.jmedchem.6b01360)
Tarlok Singh Banipal,, Amandeep Kaur, Imran A. Khan, and Parampaul Kaur Banipal, Exploring the thermodynamics and conformational aspects of nicotinic acid binding with bovine serum albumin: a detailed calorimetric, spectroscopic and molecular docking study, RSC Advances, 2016, 6, 34754-69. (DOI: 10.1039/C5RA28028A)
H. Deol, S. Pramanik, Manoj Kumar, Imran A. Khan, Vandana Bhalla, Supramolecular Ensemble of a TICT-AIEE Active Pyrazine Derivative and CuO NPs: A Potential Photocatalytic System for Sonogashira Couplings. ACS Catalysis, 2016 6(6), 3771-3783. (DOI: 10.1021/acscatal.6b00393)
Chandra S. Azad, Imran A. Khan, and Anudeep K. Narula. Organocatalyzed asymmetric Michael addition by an efficient bifunctional carbohydrate-thiourea hybrid with mechanistic DFT analysis Org. Biomol. Chem., 2016, 14, 11454-61. (DOI: 10.1039/C6OB02158A, as communicating author)
Amandeep Kaur, Imran A. Khan, Parampaul K. Banipal, Tarlok S. Banipal. Deciphering the complexation process of a fluoroquinolone antibiotic, levofloxacin, with bovine serum albumin in the presence of additives Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 191, 259-270. (DOI: 10.1016/j.saa.2017.10.017)
ResearcherID Publications
Year Title Author(s) Source Volume