Home / Seminar & Event /Past Seminars / (342) Supramolecular Chemistry In Vivo; Biomimetic Cyclodextrin Complexes That Function Well in the Biological Fields
Home / Seminar & Event /Past Seminars / (342) Supramolecular Chemistry In Vivo; Biomimetic Cyclodextrin Complexes That Function Well in the Biological Fields
(342) Supramolecular Chemistry In Vivo; Biomimetic Cyclodextrin Complexes That Function Well in the Biological Fields
Seminar: (342) Supramolecular Chemistry In Vivo; Biomimetic Cyclodextrin Complexes That Function Well in the Biological Fields
Speaker: Prof. Hiroaki Kitagishi, Associate professor, Department of Molecular Chemistry and Biochemistry, Doshisha University, Kyoto, Japan
Time: 2019-01-11 10:30 to 2019-01-11 11:30
Venue: Meeting room (406), Building 24
Organizer:

SPST


Abstract:

Cyclodextrin (CD) is a well-known supramolecular host molecule that function in aqueous solution. Since we have synthesized a biomimetic myoglobin model complex, hemoCD, composed of a methylated CD dimer and iron(II)porphyrin in 2005,[1] we have been trying to apply hemoCD in vivo as (1) artificial oxygen carrier,[2] (2) carbon monoxide (CO) scavenger,[3] (3) PDT reagent,[4] and so on.






          In the lecture, I will introduce first basic chemistry of supramolecular CD complexes with porphyrins in the biological fields as well as in water. And then I will show several in vivo application researches on hemoCD.


 

Brief Biography:

EDUCATION:

2001:   Bachelor of Engineering, Doshisha University

2003:   Master of Engineering, Nara Institute Science & Technology

Supervisor: Prof. Yoshiaki Kobuke

2006:   Philosophiae Doctor (Ph. D.), Doshisha University

Supervisor: Prof. Koji Kano

 

PROFESSIONAL EXPERIENCE:

2006–2008:     Postdoctoral Fellow at Osaka University

Collaborator: Prof. Takashi Hayashi

2008–2014:     Assistant Professor at Doshisha University

Collaborator: Prof. Koji Kano

2009–2010:     Guest Researcher at The Scripps Research Institute

Collaborator: Prof. M. G. Finn

2014–Present: Associate Professor at Doshisha University (Principal Investigator)

 

RESEARCH FIELD: Supramolecular Chemistry, Organic Chemistry, Bioinorganic Chemistry, Biological Chemistry

 

PUBLICATION: 57 original papers including J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Commun., Chem. Asian J. etc.


(342) Supramolecular Chemistry In Vivo; Biomimetic Cyclodextrin Complexes That Function Well in the Biological Fields
Seminar: (342) Supramolecular Chemistry In Vivo; Biomimetic Cyclodextrin Complexes That Function Well in the Biological Fields
Speaker: Prof. Hiroaki Kitagishi, Associate professor, Department of Molecular Chemistry and Biochemistry, Doshisha University, Kyoto, Japan
Time: 2019-01-11 10:30 to 2019-01-11 11:30
Venue: Meeting room (406), Building 24
Organizer:

SPST


Abstract:

Cyclodextrin (CD) is a well-known supramolecular host molecule that function in aqueous solution. Since we have synthesized a biomimetic myoglobin model complex, hemoCD, composed of a methylated CD dimer and iron(II)porphyrin in 2005,[1] we have been trying to apply hemoCD in vivo as (1) artificial oxygen carrier,[2] (2) carbon monoxide (CO) scavenger,[3] (3) PDT reagent,[4] and so on.






          In the lecture, I will introduce first basic chemistry of supramolecular CD complexes with porphyrins in the biological fields as well as in water. And then I will show several in vivo application researches on hemoCD.


 

Brief Biography:

EDUCATION:

2001:   Bachelor of Engineering, Doshisha University

2003:   Master of Engineering, Nara Institute Science & Technology

Supervisor: Prof. Yoshiaki Kobuke

2006:   Philosophiae Doctor (Ph. D.), Doshisha University

Supervisor: Prof. Koji Kano

 

PROFESSIONAL EXPERIENCE:

2006–2008:     Postdoctoral Fellow at Osaka University

Collaborator: Prof. Takashi Hayashi

2008–2014:     Assistant Professor at Doshisha University

Collaborator: Prof. Koji Kano

2009–2010:     Guest Researcher at The Scripps Research Institute

Collaborator: Prof. M. G. Finn

2014–Present: Associate Professor at Doshisha University (Principal Investigator)

 

RESEARCH FIELD: Supramolecular Chemistry, Organic Chemistry, Bioinorganic Chemistry, Biological Chemistry

 

PUBLICATION: 57 original papers including J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Commun., Chem. Asian J. etc.