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Home / News / Jon Antilla Team Has Made Significant Progress in the Asymmetric Research
Jon Antilla Team Has Made Significant Progress in the Asymmetric Research

Professor Jon Antilla of SPST at Tianjin University recently published a academic paper in Angewandte Chemie, named “Chiral phosphoric acid-catalyzed asymmetric synthesis of hetero-triarylmethanes from racemic indolyl alcohols”. (DOI: 10.1002/anie.201804330). The first author is PhD student Caizhen Yue, and foreign expert Jon Antilla is the advising professor.

Optically active hetero-triarylmethanes are very important structural motifs in natural products, biological active molecules and synthetic materials. Therefore, the development of efficient strategies for enantioenriched hetero-triarylmethane derivatives is of great interest to the synthetic community. This study designed a direct and broadly applicable synthetic strategy for this important structural motif. And this flexible activation mode and novel reactivity of diarylmethanols expand the synthetic potential of chiral phosphoric acids.

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Jon Antilla Team Has Made Significant Progress in the Asymmetric Research

Professor Jon Antilla of SPST at Tianjin University recently published a academic paper in Angewandte Chemie, named “Chiral phosphoric acid-catalyzed asymmetric synthesis of hetero-triarylmethanes from racemic indolyl alcohols”. (DOI: 10.1002/anie.201804330). The first author is PhD student Caizhen Yue, and foreign expert Jon Antilla is the advising professor.

Optically active hetero-triarylmethanes are very important structural motifs in natural products, biological active molecules and synthetic materials. Therefore, the development of efficient strategies for enantioenriched hetero-triarylmethane derivatives is of great interest to the synthetic community. This study designed a direct and broadly applicable synthetic strategy for this important structural motif. And this flexible activation mode and novel reactivity of diarylmethanols expand the synthetic potential of chiral phosphoric acids.

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