Study Sheds Light on the Mechanism of Diamide Insecticides and Associated Resistance
2024/11/18
Recently, a research team led by Professor Yuchi Zhiguang from Tianjin University, along with collaborators, published a study in Nature Communications titled "Cryo-EM Structures of Ryanodine Receptors and Diamide Insecticides Reveal the Mechanisms of Selectivity and Resistance" (https://doi.org/10.1038/s41467-024-53490-0).Insects demonstrate extraordinary adaptability in dynamic ecosystems, thanks ...
SPST Faculty Develop Novel Ferroptotis-Targeting Ovarian Cancer Therapy
2024/10/08
Ferroptosis has been recognized as a promising therapeutic strategy for cancer due to its unique mechanism of action. However, the upregulation of stearoyl-CoA desaturase 1 (SCD1) in ovarian cancer leads to resistance to ferroptotic therapy. Zinc ion (Zn2+) serves as the cofactor of SCD1. It was hypothesized that selective deprivation of Zn2+ from SCD1 could sensitize ferroptotic ovarian cancer therapy....
2024/09/03
On August 21-23, 2024, the 2024 International Value-Based Healthcare Conference was held in Singapore. Prof. Wu Jing, vice secretary (in charge of party affairs) and vice president of SPST, and Dr. Xie Shitong, associate researcher in the Department of health and pharmacy administration, attended the conference as special guests. They also engaged in academic exchanges with top international un...
Jiuzhoutong Pharmaceutical Co., Ltd visited SPST
2024/09/02
On August 1st, 2024, Jiuzhoutong Pharmaceutical Co., Ltd. Visited SPST, accompanied by Dean of SPST, Liu Xiuyun, and the Deputy Dean of SPST, Du Yunfei.Through exchanges and research, both sides look forward to further enhancing exchanges and cooperation and jointly assisting the health industry.
Delegation of Indian Scientists Visits SPST
2024/09/02
On June 28th, a delegation of Indian scientists consisting Professor Soumyajit Roy of India Academy of Science, Education and Research, Kolkata; Dr. Nageswara Rao Pulipati of Bycus Therapeutics Pvt. Ltd, India; Professor Kalpesh Vasant Bhavsar of National Centre for Nanoscience and Nanotechnology, University of Mumbai; Mr. Vithal Kumar.L, manager of technology transfer office, IKP Knowledge Park, Hyderabad ...
Professor Gao Wenyuan’s Team Makes Progress in the Biological Control of Astragalus Memeranaceus
2024/03/11
Recently, the team of Professor Gao Wenyuan in the School of Pharmaceutical Science and Technology (SPST) of Tianjin University developed biological antifungal agent for root rot. The relevant research is published on Chemical Engineering Journal as "ZnO-S.cerevisiae: An effective growth promoter of Astragalus memeranaceus and nano-antifungal agent against Fusarium oxysporum".Su Yaowu, master student ...
2024/02/06
Following surgery, tumor recurrence is a common concern that can be managed through immunotherapy. Nevertheless, the efficacy of such therapy is restricted. Emerging research has indicated that cellular pyroptosis may trigger long-lasting hyperinflammation, which can assist the immune system in effectively eliminating tumor cells over an extended period. Consequently, upholding the localized mi...
Reversing Ferroptosis Resistance in Breast Cancer via Tailored Lipid and Iron Presentation
2023/12/11
Cancer resistance is often associated with the presence of persister cells and the polarization of cancer cells towards a mesenchymal state. Therefore, ferroptotic cancer therapy has gained extensive attention because it is potent to eradicate resistant cancers that are refractory to conventional apoptosis-based approaches. Tailored phospholipids (arachidonoyl phosphatidylethanolamine/PE-AA) ar...
SPST Teacher Attends 7th National Academic Conference on Analytical Pharmacology
2023/11/09
From October 20 to 22, the 7th National Academic Conference on Analytical Pharmacology was held in Hangzhou. Dr. Xiangjun Meng, an associate professor from School of Pharmaceutical Science and Technology, Tianjin University, was invited to attend this conference.The conference was organized by the Analytical Pharmacology Committee of the Chinese Pharmacological Society. With the theme of "Towar...
2023/11/09
Heavy metal pollution has become a significant global environmental issue, with lead being one of the primary contaminants. Lead pollution primarily originates from human activities, particularly mining, manufacturing, and the combustion of fossil fuels, which releases lead into the environment and ultimately poses risks to human health. However, issues such as long-term exposure to lead and ot...
