15th SPST Sub-session of 2023 Doctoral Academic Forum of Tianjin University Held
2023/10/23
On October 19, 2023 Doctoral Academic Forum of Tianjin University opened in the lecture hall on the second floor of Science Library.Prof. Chang Jin and Prof. Zhang Xiaodong (Forum Supervisors from Tianjin University), Secretary of the Party Committee of the School of Pharmaceutical Science and Technology (SPST) Zhang Ling, Vice Party Secretary Li Nan, Associate Deans of SPST Peter Robert Taylor...
2023/10/16
Among known click chemistry, sulfur(VI) fluoride exchange (SuFEx) reaction, a new generation click chemistry, in which the S–F bond reacts readily with silyl-protected phenols, phenolates or amines. In 2019, Han Zuilhof’s group discovered that SuFEx reaction is intrinsically enantiospecific click reaction as a chiral S(VI) center reacts exclusively with inversion of configuration. The SuFEx r...
Radical Trapping Chiral Polymers to Address Uncontrolled Inflammation
2023/06/23
Uncontrolled inflammation is associated with the pathophysiology of numerous diseases. The hyperinflammatory conditions are often accompanied with multi-organ system failure that correlates with a high mortality. Currently, there has been no effective approaches for addressing this clinical unmet need. It is well believed that there exists a positive feedback loop between pro-inflammatory signa...
SPST won the “2022 Outstanding Doctoral Dissertation Award of Tianjin”
2023/05/10
Association of Tianjin Graduation Education recently announced the recipients of “2022 Outstanding Master's and Doctoral Dissertation Award”. Dr. Dazhi Liu, a SPST alumnus, was honored with this prestigious award for his PhD dissertation under the supervision of Chair Professor Yan Zhang, titled “Identification and Characterization of Bacterial Enzymes Involved in Anaerobic Metabolism of A...
【Science and Technology Daily】Creativity, an Engine to Sustain Development
2023/05/08
Source: Science and Technology Daily | 2023-05-04 10:39:21 | Author: LONG Yun & BI WeiziProfessor Peter Taylor. (COURTESY PHOTO)By LONG Yun & BI WeiziIn contrast to the current focus on machine learning and AI, which have their own benefits, British scientist Peter Taylor said in a recent interview with Science and Technology Daily that, "Creativity is a crucial advantage that humans...
Chiral Iron-Chelating Polymers for Alleviating Adriamycin Cardiotoxicity
2023/04/19
The clinical application of adriamycin has been hindered by the notorious irreversible cardiomyopathy that is dependent on the cumulative dose. It is reported that the maximum tolerated dose of adriamycin is 550 mg/m2, significantly affecting patient compliance and therapeutic outcomes. In 2019, the mechanisms of adriamycin-induced cardiotoxicity were revealed due to ferroptosis, which opens ...
Student Officers for Lab Safety Meeting Held in SPST
2023/03/05
On the afternoon of March 2, SPST held a meeting of Student Officers for Lab Safety in Room 205 of the 24th Building. The meeting was organized by the safety group of SPST and all members including Yunfei Du, Yong Zhang, Minjie Guo, and Yuru Ma participated the meeting. Ling Zhang, the Party Secretary of SPST, attended the meeting and delivered a speech. The meeting was presided over by Yuru Ma...
2023/02/13
On February 6-7, 2023, Professor Gao Wenyuan, a leader in the Chinese Medicine Discipline in SPST, visited the ISO/TC249 Secretariat and Chairman Yuandong Shen. He Yi, Dean of Tasly Research Institute, Professor Li Xia of the School of Pharmacy of Tianjin University, and Bai Xiaoli, Director of the Standardization Research Center of Tasly Research Institute, were accompanied by him. The Secreta...
Nan Li's group has made new progress in the treatment of magnetic response triggered tumor immunity
2023/02/11
Immunotherapy is a promising therapeutic tool for tumor treatment. However, the lack of immune response has a serious impact on the effectiveness of treatment. Recent studies have revealed that pro-inflammatory factors produced through pyroptosis can induce an inflammation-based immune response in the treated individual in a variety of active or passive ways, thus exerting the immune system's k...
Nan Li's group made new progress in the treatment of inflammatory bowel diseases
2023/01/14
Inflammatory bowel diseases (IBDs), such as Crohn’s disease (CD) and ulcerative colitis (UC), are chronic intestinal inflammatory diseases that occur worldwide and influence millions of people. Intestinal milieu disorders are strongly related to the occurrence of IBDs, which results from mucosa destruction, epithelium disruption and tight junction (TJ) proteins loss. Excess of H2S in the intes...
2022/12/07
On Friday evening December 2, 2022, Chinese Consul General to Zurich and for the Principality of Liechtenstein, ZHAO Qinghua, hosted a reception and dinner for Swiss foreign experts who were China National Friendship Award winners. At a reception before the dinner Professor Jay Siegel, Dean Emeritus-SPST, and Professor Kim Baldridge met with CG ZHAO to enjoy an exhibition of the past decade of ...
Nan Li's lab developed the nano-matchbox for tumor therapy
2022/06/11
Nowadays, associate professor Nan Li and her team from the School of Pharmaceutical Science and Technology published an article on novel nanomaterials for combined photothermal therapy (PTT) and ferrotherapy (FPT) in tumor treatment in Acta Pharmaceutica Sinica B, a leading journal of Chinese Science and Technology Journals. The title of the article is ‘Iron-based and BRD4-downregulated strate...
2022/05/23
On May 16-17, 2022, Professor Gao Wenyuan, a talented professor of Tianjin University and a post scientist in the National Traditional Chinese Medicine Industry Technology System, attended the 2022 (Second) International Summit Forum on Traditional Medicine Research and gave a conference report, which was widely praised.
SPST's "National Award Winner" experience exchange meeting
2022/05/23
On May 5, 2022, the Graduate Student Association of SPST, together with the Second Party Branch of the Class of 2021, successfully held an experience exchange meeting of "National Award Greats" through Tencent Conference.The speakers were Li Wen, Zhao Dongqing and Yu Zhenyang, who shared some insights and practical experiences on their growth paths from different aspects of study, research, emp...
SPST successfully held "job hunter says" sharing sessions of outstanding graduates in the workplace
2022/05/23
On the evening of April 4th, the Graduate Student Association held "job hunter says" through the Tencent Conference to help students understand the employment direction and environment of the pharmacy major.Ms. Haiying Wang, the counselor of the SPST, presided over the online workplace experience sharing meeting and invited two outstanding graduates, Mengying Liu and Yahui Jing.Mengying Liu is ...
SPST Convene A Review Meeting for the Undergraduate Innovation Projects
2022/05/11
SPST Convene A Review Meeting for the Undergraduate Innovation ProjectsDU Yunfei, LIU ZichuanSynthesis and Activity Studies of Deuterated Melatonin CHEN RuibingA Tool for Precision Medicine - the Development of a Membrane Proteomics Strategy to Facilitate Personalized Diagnosis in Kidney Cancer ZHAO YanjunStudy of siRNA Nanocarrier Based on Ovarian Cancer Target MU Xin, WANG YiwenInterplay Be...
2022/05/11
SPST held faculty meeting in meeting room 207 on May 10th.During the meeting, we conveyed the spirit of the recent party committee meetings, learned the contents of TJU 3rd Talent Work Meeting, and reported the progress of several important school affairs.The meeting was hosted by Zhang Ling, deputy party secretary& associate dean, associate deans Du Yunfei, Zhou Yan and Chen Le gave the repo...
Mechano-Responsive Polymers for Ferroptosis Therapy
2022/04/29
Ferroptosis is crucial for many physiological and pathological processes, and hence it has been employed for treating a plethora of (resistant) tumors. On-demand iron delivery or modulation of iron metabolism is a typical approach for ferroptosis induction or sensitization. However, the tumor-specific delivery of Fe2+ is highly challenging. The emergence of ferrocene as a mechanophore offers a ...
2022/04/20
Autophagy, a specific degradation pathway depends on lysosome in eucaryon, has emerging significance in many diseases. Specifically, autophagy supplies the demand for cellular energy and reduces the sensitivity of tumor cells thus enhance the drug resistance in cancer treatments. Hence, autophagy inhibition coule be a potential method for cancer treatment. In addition, autophagy plays a role de...
