Jiuzhoutong Pharmaceutical Co., Ltd visited SPST
2024/09/02
On August 1st, 2024, Jiuzhoutong Pharmaceutical Co., Ltd. Visited SPST, accompanied by Dean of SPST, Liu Xiuyun, and the Deputy Dean of SPST, Du Yunfei.Through exchanges and research, both sides look forward to further enhancing exchanges and cooperation and jointly assisting the health industry.
Delegation of Indian Scientists Visits SPST
2024/09/02
On June 28th, a delegation of Indian scientists consisting Professor Soumyajit Roy of India Academy of Science, Education and Research, Kolkata; Dr. Nageswara Rao Pulipati of Bycus Therapeutics Pvt. Ltd, India; Professor Kalpesh Vasant Bhavsar of National Centre for Nanoscience and Nanotechnology, University of Mumbai; Mr. Vithal Kumar.L, manager of technology transfer office, IKP Knowledge Par...
Professor Gao Wenyuan’s Team Makes Progress in the Biological Control of Astragalus Memeranaceus
2024/03/11
Recently, the team of Professor Gao Wenyuan in the School of Pharmaceutical Science and Technology (SPST) of Tianjin University developed biological antifungal agent for root rot. The relevant research is published on Chemical Engineering Journal as "ZnO-S.cerevisiae: An effective growth promoter of Astragalus memeranaceus and nano-antifungal agent against Fusarium oxysporum".Su Yaowu, master s...
SPST Faculty Develop Novel Ferroptptic Melanoma Therapy
2024/02/26
Ferroptotic cancer therapy has been extensively investigated since the coining of the ferroptosis concept. However, the therapeutic efficacy of ferroptosis induction in heterogeneous and plastic melanoma has been compromised because the melanocytic and transitory cell subpopulation is resistant to iron-dependent oxidative stress. The Research Group at SPST recently reported a phenotype-altering...
2024/02/06
Following surgery, tumor recurrence is a common concern that can be managed through immunotherapy. Nevertheless, the efficacy of such therapy is restricted. Emerging research has indicated that cellular pyroptosis may trigger long-lasting hyperinflammation, which can assist the immune system in effectively eliminating tumor cells over an extended period. Consequently, upholding the localized mi...
Reversing Ferroptosis Resistance in Breast Cancer via Tailored Lipid and Iron Presentation
2023/12/11
Cancer resistance is often associated with the presence of persister cells and the polarization of cancer cells towards a mesenchymal state. Therefore, ferroptotic cancer therapy has gained extensive attention because it is potent to eradicate resistant cancers that are refractory to conventional apoptosis-based approaches. Tailored phospholipids (arachidonoyl phosphatidylethanolamine/PE-AA) ar...
SPST Teacher Attends 7th National Academic Conference on Analytical Pharmacology
2023/11/09
From October 20 to 22, the 7th National Academic Conference on Analytical Pharmacology was held in Hangzhou. Dr. Xiangjun Meng, an associate professor from School of Pharmaceutical Science and Technology, Tianjin University, was invited to attend this conference.The conference was organized by the Analytical Pharmacology Committee of the Chinese Pharmacological Society. With the theme of "Towar...
2023/11/09
Heavy metal pollution has become a significant global environmental issue, with lead being one of the primary contaminants. Lead pollution primarily originates from human activities, particularly mining, manufacturing, and the combustion of fossil fuels, which releases lead into the environment and ultimately poses risks to human health. However, issues such as long-term exposure to lead and ot...
Using Probiotics to Alleviate Insulin Resistance Uncovers New Treatment Pathways
2023/11/03
Insulin resistance plays a key role in type 2 diabetes research, and a high-sugar diet is often considered one of its main triggers. Recently, Professor Wang Yiwen’s research team at the School of Pharmaceutical Science and Technology successfully used the fruit fly (Drosophila melanogaster), as a model to explore the potential role of gut microbiota in insulin resistance.The study results sho...
2023/10/26
Chiral recognition is an important topic in modern drug research. Two enantiomers of chiral drugs may present different pharmacodynamics and pharmacokinetic properties. For example, one enantiomer has pharmacological activity, while the other is less active or even toxic. The physical and chemical properties of the two enantiomers are very similar, and their separation directly depends on the c...
15th SPST Sub-session of 2023 Doctoral Academic Forum of Tianjin University Held
2023/10/23
On October 19, 2023 Doctoral Academic Forum of Tianjin University opened in the lecture hall on the second floor of Science Library.Prof. Chang Jin and Prof. Zhang Xiaodong (Forum Supervisors from Tianjin University), Secretary of the Party Committee of the School of Pharmaceutical Science and Technology (SPST) Zhang Ling, Vice Party Secretary Li Nan, Associate Deans of SPST Peter Robert Taylor...
2023/10/16
Among known click chemistry, sulfur(VI) fluoride exchange (SuFEx) reaction, a new generation click chemistry, in which the S–F bond reacts readily with silyl-protected phenols, phenolates or amines. In 2019, Han Zuilhof’s group discovered that SuFEx reaction is intrinsically enantiospecific click reaction as a chiral S(VI) center reacts exclusively with inversion of configuration. The SuFEx r...
Radical Trapping Chiral Polymers to Address Uncontrolled Inflammation
2023/06/23
Uncontrolled inflammation is associated with the pathophysiology of numerous diseases. The hyperinflammatory conditions are often accompanied with multi-organ system failure that correlates with a high mortality. Currently, there has been no effective approaches for addressing this clinical unmet need. It is well believed that there exists a positive feedback loop between pro-inflammatory signa...
SPST won the “2022 Outstanding Doctoral Dissertation Award of Tianjin”
2023/05/10
Association of Tianjin Graduation Education recently announced the recipients of “2022 Outstanding Master's and Doctoral Dissertation Award”. Dr. Dazhi Liu, a SPST alumnus, was honored with this prestigious award for his PhD dissertation under the supervision of Chair Professor Yan Zhang, titled “Identification and Characterization of Bacterial Enzymes Involved in Anaerobic Metabolism of A...
【Science and Technology Daily】Creativity, an Engine to Sustain Development
2023/05/08
Source: Science and Technology Daily | 2023-05-04 10:39:21 | Author: LONG Yun & BI WeiziProfessor Peter Taylor. (COURTESY PHOTO)By LONG Yun & BI WeiziIn contrast to the current focus on machine learning and AI, which have their own benefits, British scientist Peter Taylor said in a recent interview with Science and Technology Daily that, "Creativity is a crucial advantage that humans...
Chiral Iron-Chelating Polymers for Alleviating Adriamycin Cardiotoxicity
2023/04/19
The clinical application of adriamycin has been hindered by the notorious irreversible cardiomyopathy that is dependent on the cumulative dose. It is reported that the maximum tolerated dose of adriamycin is 550 mg/m2, significantly affecting patient compliance and therapeutic outcomes. In 2019, the mechanisms of adriamycin-induced cardiotoxicity were revealed due to ferroptosis, which opens ...
Student Officers for Lab Safety Meeting Held in SPST
2023/03/05
On the afternoon of March 2, SPST held a meeting of Student Officers for Lab Safety in Room 205 of the 24th Building. The meeting was organized by the safety group of SPST and all members including Yunfei Du, Yong Zhang, Minjie Guo, and Yuru Ma participated the meeting. Ling Zhang, the Party Secretary of SPST, attended the meeting and delivered a speech. The meeting was presided over by Yuru Ma...
2023/02/13
On February 6-7, 2023, Professor Gao Wenyuan, a leader in the Chinese Medicine Discipline in SPST, visited the ISO/TC249 Secretariat and Chairman Yuandong Shen. He Yi, Dean of Tasly Research Institute, Professor Li Xia of the School of Pharmacy of Tianjin University, and Bai Xiaoli, Director of the Standardization Research Center of Tasly Research Institute, were accompanied by him. The Secreta...
Nan Li's group has made new progress in the treatment of magnetic response triggered tumor immunity
2023/02/11
Immunotherapy is a promising therapeutic tool for tumor treatment. However, the lack of immune response has a serious impact on the effectiveness of treatment. Recent studies have revealed that pro-inflammatory factors produced through pyroptosis can induce an inflammation-based immune response in the treated individual in a variety of active or passive ways, thus exerting the immune system's k...
