Using Probiotics to Alleviate Insulin Resistance Uncovers New Treatment Pathways
2023/11/03
Insulin resistance plays a key role in type 2 diabetes research, and a high-sugar diet is often considered one of its main triggers. Recently, Professor Wang Yiwen’s research team at the School of Pharmaceutical Science and Technology successfully used the fruit fly (Drosophila melanogaster), as a model to explore the potential role of gut microbiota in insulin resistance.The study results sho...
2023/10/26
Chiral recognition is an important topic in modern drug research. Two enantiomers of chiral drugs may present different pharmacodynamics and pharmacokinetic properties. For example, one enantiomer has pharmacological activity, while the other is less active or even toxic. The physical and chemical properties of the two enantiomers are very similar, and their separation directly depends on the c...
15th SPST Sub-session of 2023 Doctoral Academic Forum of Tianjin University Held
2023/10/23
On October 19, 2023 Doctoral Academic Forum of Tianjin University opened in the lecture hall on the second floor of Science Library.Prof. Chang Jin and Prof. Zhang Xiaodong (Forum Supervisors from Tianjin University), Secretary of the Party Committee of the School of Pharmaceutical Science and Technology (SPST) Zhang Ling, Vice Party Secretary Li Nan, Associate Deans of SPST Peter Robert Taylor...
2023/10/16
Among known click chemistry, sulfur(VI) fluoride exchange (SuFEx) reaction, a new generation click chemistry, in which the S–F bond reacts readily with silyl-protected phenols, phenolates or amines. In 2019, Han Zuilhof’s group discovered that SuFEx reaction is intrinsically enantiospecific click reaction as a chiral S(VI) center reacts exclusively with inversion of configuration. The SuFEx r...
Radical Trapping Chiral Polymers to Address Uncontrolled Inflammation
2023/06/23
Uncontrolled inflammation is associated with the pathophysiology of numerous diseases. The hyperinflammatory conditions are often accompanied with multi-organ system failure that correlates with a high mortality. Currently, there has been no effective approaches for addressing this clinical unmet need. It is well believed that there exists a positive feedback loop between pro-inflammatory signa...
SPST won the “2022 Outstanding Doctoral Dissertation Award of Tianjin”
2023/05/10
Association of Tianjin Graduation Education recently announced the recipients of “2022 Outstanding Master's and Doctoral Dissertation Award”. Dr. Dazhi Liu, a SPST alumnus, was honored with this prestigious award for his PhD dissertation under the supervision of Chair Professor Yan Zhang, titled “Identification and Characterization of Bacterial Enzymes Involved in Anaerobic Metabolism of A...
【Science and Technology Daily】Creativity, an Engine to Sustain Development
2023/05/08
Source: Science and Technology Daily | 2023-05-04 10:39:21 | Author: LONG Yun & BI WeiziProfessor Peter Taylor. (COURTESY PHOTO)By LONG Yun & BI WeiziIn contrast to the current focus on machine learning and AI, which have their own benefits, British scientist Peter Taylor said in a recent interview with Science and Technology Daily that, "Creativity is a crucial advantage that humans...
Chiral Iron-Chelating Polymers for Alleviating Adriamycin Cardiotoxicity
2023/04/19
The clinical application of adriamycin has been hindered by the notorious irreversible cardiomyopathy that is dependent on the cumulative dose. It is reported that the maximum tolerated dose of adriamycin is 550 mg/m2, significantly affecting patient compliance and therapeutic outcomes. In 2019, the mechanisms of adriamycin-induced cardiotoxicity were revealed due to ferroptosis, which opens ...
Student Officers for Lab Safety Meeting Held in SPST
2023/03/05
On the afternoon of March 2, SPST held a meeting of Student Officers for Lab Safety in Room 205 of the 24th Building. The meeting was organized by the safety group of SPST and all members including Yunfei Du, Yong Zhang, Minjie Guo, and Yuru Ma participated the meeting. Ling Zhang, the Party Secretary of SPST, attended the meeting and delivered a speech. The meeting was presided over by Yuru Ma...
2023/02/13
On February 6-7, 2023, Professor Gao Wenyuan, a leader in the Chinese Medicine Discipline in SPST, visited the ISO/TC249 Secretariat and Chairman Yuandong Shen. He Yi, Dean of Tasly Research Institute, Professor Li Xia of the School of Pharmacy of Tianjin University, and Bai Xiaoli, Director of the Standardization Research Center of Tasly Research Institute, were accompanied by him. The Secreta...
