2022/04/20
Autophagy, a specific degradation pathway depends on lysosome in eucaryon, has emerging significance in many diseases. Specifically, autophagy supplies the demand for cellular energy and reduces the sensitivity of tumor cells thus enhance the drug resistance in cancer treatments. Hence, autophagy inhibition coule be a potential method for cancer treatment. In addition, autophagy plays a role de...
eLife | Prof. Zhiguang Yuchi Group Revealed a Mechanism of Dilated Cardiomyopathy
2022/03/23
Dilated cardiomyopathy (DCM) is the most common type of cardiomyopathy and one of the leading causes of heart failure (HF). Several mutations identified in phospholamban (PLN) have been linked to familial DCM and HF, yet the underlying molecular mechanism remains controversial. Under physiological conditions, PLN interacts with sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) and regulates calci...
SPST was Approved Six 2021 Tianjin Graduate Research and Innovation Projects
2022/03/04
PhD ProgramJIANG Na The single cell and cell type resolved proteomics profiling of the tumor microenvironment in clear cell renal cell carcinoma BAI HuiThe application of multi-mode chiral stationary phases in the quality control of chiral drugs LI RuilinThe hepatic-targeted, luteolin loaded nanoparticles construction and its mechanism on obesity SHI HaofengSulfoxide/Selenium sulfoxide medited ...
2022/03/04
At 9:00 on the 21st, the forum opened in the lecture hall on the second floor of science library. Director of Education Office in Graduate School Qi Wei, associate dean and vice secretary Zhang Ling, associate dean Du Yunfei, associate dean Zhou Yan, vice secretary Chen Le and some professors of SPST attended the opening ceremony, which fully reflected the great importance of the university an...
Review Article on Triterpene Saponins Produced by Microorganisms Published
2021/02/03
Recently, Professor Gao Wenyuan’s research group from the School of Pharmaceutical Science and Technology (SPST) published an online article Endophytes, Biotransforming Microorganisms, and Engineering Microbial Factories for Production of Triterpenoid Saponins in the well-known biotechnology journal Critical reviews in biotechnology. This thesis systematically discussed the potential mechanism...
2021/01/27
Prof. Haixia Chen's research group from the School of Pharmaceutical Science and Technology published a review paper "The structure-mechanism relationship and mode of actions of antimicrobial peptides: A review" (https://doi.org/10.1016/j.tifs.2021.01.005) in the well-known international journal Trends in Food Science & Technology on the basis of a large quantities of previous researches on bio...
2020/11/05
The opening ceremony was held in Room 103 of the Building 26 at 9:00 a.m., Oct. 27th. Prof. Qi Wei, Director of Graduate School Development Office, Prof. Ma Youguang and Prof. Huang Yanshun, supervisory experts of Graduate School Development Office, Prof. Jay Siegel, dean of SPST, Ms. Cuiling Feng, secretary of the Party Committee of SPST, and some professors of SPST attended the opening ceremo...
The Discovery of Hepatitis C Virus Wins 2020 Nobel Prize in Physiology or Medicine
2020/10/09
The 2020 Nobel Prize in Physiology or Medicine is awarded to Harvey J. Alter (NIH, USA), Michael Houghton (University of Alberta, Canada) and Charles M. Rice (Rockefeller University, USA) for the discovery of Hepatitis C virus (HCV). Hepatitis is liver inflammation that is mainly caused by viral infections, although drugs, toxins, alcohol, and autoimmune diseases are also important causes. In 1...
From Yogurt to Genetic Scissors: Nobel Recognition for CRISPR
2020/10/09
The Nobel Prize in Chemistry was jointly awarded to Emmanuelle Charpentier and Jennifer Doudna for their CRISPR work. It is the first time a science Nobel has been awarded to two women. The function of CRISPR was first identified in 2007 by researchers at the Danish yogurt company DANISCO. Lactobacillus responsible for yogurt fermentation are susceptible to viral infection, but they discovered ...
3rd TJU Pharmacoeconomics Research and Practice Training Course Held
2020/09/01
From August 14 to 16, 2020, the 3rd Tianjin University Pharmacoeconomics Research and Practice Training Course was successfully held at Tianjin University. Sponsored by Tianjin University and undertaken by the School of Pharmaceutical Science and Technology (SPST), the course was taught by SPST staff members including Professor Wu Jing, Lecturer He Xiaoning, Dr. Xie Shitong, and Dr. Liu Jia who...
